ArticleCurrent prostate reports2008
Inflammatory Mechanisms Associated with Prostatic Inflammation and Lower Urinary Tract Symptoms.
Article in Current prostate reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Statin Use, Serum Lipids, and Prostate Inflammation in Men with a Negative Prostate Biopsy: Results from the REDUCE Trial.Cancer prevention research (Philadelphia, Pa.) · 2017Trial
- Peripheral serotonin contributes to testosterone and estradiol induced urinary voiding dysfunction in adult male mice.American journal of clinical and experimental urology · 2026Article
- Elevated Peripheral White Blood Cell Count and Lower Urinary Tract Symptom Risk: A Population-Based Cross-Sectional Study of Chinese Men.Research and reports in urology · 2026Article
- Asiatic acid mitigates testosterone-induced benign prostatic hyperplasia in rats via activation of PPAR-γ.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Association between trichomoniasis and prostate and bladder diseases: a population-based case-control study.Scientific reports · 2022Article
- Signaling Role of Adipocyte Leptin in Prostate Cell Proliferation Induced by Trichomonas vaginalis.The Korean journal of parasitology · 2021Article
- IL-27/IL-27RA signaling may modulate inflammation and progression of benign prostatic hyperplasia via suppressing the LPS/TLR4 pathway.Translational cancer research · 2020Article
- Dietary Carcinogens and DNA Adducts in Prostate Cancer.Advances in experimental medicine and biology · 2019Review
- CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling.PloS one · 2016Article
- Article
- Inflammatory Signaling Involved in High-Fat Diet Induced Prostate Diseases.Journal of urology and research · 2015Article
- Modulatory effect of silymarin on inflammatory mediators in experimentally induced benign prostatic hyperplasia: emphasis on PTEN, HIF-1α, and NF-κB.Naunyn-Schmiedeberg's archives of pharmacology · 2014Article
- Beta-catenin is elevated in human benign prostatic hyperplasia specimens compared to histologically normal prostate tissue.American journal of clinical and experimental urology · 2014Article
- Increased risk of benign prostate hyperplasia in sleep apnea patients: a nationwide population-based study.PloS one · 2014Article
- Prostatic fibrosis, lower urinary tract symptoms, and BPH.Nature reviews. Urology · 2013Review
- Effect of high-dose intravenous vitamin C on inflammation in cancer patients.Journal of translational medicine · 2012Article
- Influence of immune inflammation on androgen receptor expression in benign prostatic hyperplasia tissue.Asian journal of andrology · 2012Article
- Article
- Nonsteroidal antiinflammatory drug use and lower urinary tract symptoms: results from the Boston area community health survey.American journal of epidemiology · 2011Article
- Are statin medications associated with lower urinary tract symptoms in men and women? Results from the Boston Area Community Health (BACH) Survey.Annals of epidemiology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Inflammation is a common finding in histologic prostate specimens obtained from aging men, and accumulating data suggest that inflammation may play an important role in the development of benign prostatic hyperplasia (BPH), and the development and progression of lower urinary tract symptoms (LUTS). Inflammatory processes may contribute to prostatic enlargement directly through stimulation of prostate growth, or, alternatively, through decreasing prostatic apoptosis. Additionally, inflammatory processes may impact other components of the urogenital tract, such as the bladder, and contribute to the LUTS that may be experienced both in the presence and in the absence of prostate enlargement. Current research therefore offers clues about converging inflammatory pathways which may be targeted to improve treatment of BPH and/or LUTS as well as identifying potential targets for prevention of these syndromes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.