Evidence map›Paper›PMID 19809534›Full record

ArticleBrain imaging and behavior2009

A Cognitive Neuroscience View of Schizophrenic Symptoms: Abnormal Activation of a System for Social Perception and Communication.

Cynthia G Wible, Alexander P Preus, Ryuichiro Hashimoto

Abstract read
In one paragraph

Article in Brain imaging and behavior, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Neural correlates of the relationship between discourse coherence and sensory monitoring in schizophrenia.Cortex; a journal devoted to the study of the nervous system and behavior · 2014
    Article
  14. Postmortem brain: an underutilized substrate for studying severe mental illness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cynthia G WibleDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Alexander P Preus
Ryuichiro Hashimoto

Funding

Auditory-verbal functional studies of schizophreniaR01MH067080 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WIBLE, CYNTHIA G · 2005 to 2009
$1.4M
NIMH NIH HHS R01 MH067080
6 · The paper itself

Abstract

We will review converging evidence that language related symptoms of the schizophrenic syndrome such as auditory verbal hallucinations arise at least in part from processing abnormalities in posterior language regions. These language regions are either adjacent to or overlapping with regions in the (posterior) temporal cortex and temporo-parietal occipital junction that are part of a system for processing social cognition, emotion, and self representation or agency. The inferior parietal and posterior superior temporal regions contain multi-modal representational systems that may also provide rapid feedback and feed-forward activation to unimodal regions such as auditory cortex. We propose that the over-activation of these regions could not only result in erroneous activation of semantic and speech (auditory word) representations, resulting in thought disorder and voice hallucinations, but could also result in many of the other symptoms of schizophrenia. These regions are also part of the so-called "default network", a network of regions that are normally active; and their activity is also correlated with activity within the hippocampal system.

Identifiers

PMID19809534
PMCPMC2757313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.