Evidence map›Paper›PMID 19808725›Full record

ReviewVascular medicine (London, England)2009

Novel markers of peripheral arterial disease.

Farhan J Khawaja, Iftikhar J Kullo

Abstract readReview
In one paragraph

Review in Vascular medicine (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  16. β-blockade: benefits beyond blood pressure reduction?Journal of clinical hypertension (Greenwich, Conn.) · 2012
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Farhan J KhawajaDepartment of Medicine, Division of Cardiovascular Diseases and the Gonda Vascular Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Iftikhar J Kullo

Funding

Proteomic Markers of ArteriosclerosisU01HL081331 · NHLBI · MAYO CLINIC ROCHESTER · PI KULLO, IFTIKHAR J · 2005 to 2008
$3.7M
Biomarkers of Peripheral Arterial DiseaseR01HL075794 · NHLBI · MAYO CLINIC ROCHESTER · PI KULLO, IFTIKHAR J · 2003 to 2007
$3.0M
NHLBI NIH HHS HL75794NHLBI NIH HHS HL81331NHLBI NIH HHS R01 HL075794NHLBI NIH HHS U01 HL081331
6 · The paper itself

Abstract

Peripheral arterial disease (PAD), a relatively common manifestation of atherosclerotic vascular disease, is associated with significant morbidity and mortality. Although conventional risk factors contribute to the onset and progression of PAD, the role of 'novel' biomarkers in pathways of inflammation, thrombosis, lipoprotein metabolism, and oxidative stress in determining susceptibility to PAD is being increasingly recognized. Validation of novel risk factors for PAD may allow earlier detection, an improved understanding of disease etiology and progression, and the development of new therapies. In this review, we discuss available evidence for associations between novel circulating markers and several aspects of PAD including disease susceptibility, progression, functional limitation, and adverse outcomes.

Indexed as

BiomarkersDisease ProgressionDisease SusceptibilityEvidence-Based MedicineHumansInflammationInflammation MediatorsLipoproteinsOxidative StressPeripheral Vascular DiseasesPredictive Value of TestsPrognosisRisk FactorsThrombosisBiomarkersInflammation MediatorsLipoproteins

Identifiers

PMID19808725
PMCPMC2901866

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.