ReviewCurrent topics in medicinal chemistry2009
The pilot phase of the NIH Chemical Genomics Center.
Review in Current topics in medicinal chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences.SLAS discovery : advancing life sciences R & D · 2020Article
- Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.SLAS discovery : advancing life sciences R & D · 2020Article
- Supporting read-across using biological data.ALTEX · 2016Article
- From QSAR to QSIIR: searching for enhanced computational toxicology models.Methods in molecular biology (Clifton, N.J.) · 2013Review
- Paradigm shift in toxicity testing and modeling.The AAPS journal · 2012Review
- Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2).MedChemComm · 2012Article
- The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics.Science translational medicine · 2011Article
- The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform.Drug discovery today · 2010Review
- Intersection of toxicogenomics and high throughput screening in the Tox21 program: an NIEHS perspective.International journal of biotechnologyArticle
- Isotonic Regression Based-Method in Quantitative High-Throughput Screenings for Genotoxicity.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
The NIH Chemical Genomics Center (NCGC) was the inaugural center of the Molecular Libraries and Screening Center Network (MLSCN). Along with the nine other research centers of the MLSCN, the NCGC was established with a primary goal of bringing industrial technology and experience to empower the scientific community with small molecule compounds for use in their research. We intend this review to serve as 1) an introduction to the NCGC standard operating procedures, 2) an overview of several of the lessons learned during the pilot phase and 3) a review of several of the innovative discoveries reported during the pilot phase of the MLSCN.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.