ArticleThe review of diabetic studies : RDS2009
Comparison of fasting glucose with post-load glucose values and glycated hemoglobin for prediction of type 2 diabetes: the Isfahan diabetes prevention study.
Article in The review of diabetic studies : RDS, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Predicting Factors for Metabolic Non-Response to a Complex Lifestyle Intervention-A Replication Analysis to a Randomized-Controlled Trial.Nutrients · 2022Trial
- The utility of diagnostic tests in the detection and prediction of glucose intolerance in the early and late postpartum period in women after gestational diabetes: a longitudinal cohort study.Diabetology & metabolic syndrome · 2021Article
- Impaired fasting glucose levels in overweight or obese subjects for screening of type 2 diabetes in Korea.The Korean journal of internal medicine · 2021Article
- Predictability of 1-h postload plasma glucose concentration: A 10-year retrospective cohort study.Journal of diabetes investigation · 2015Article
- Platelet mitochondrial dysfunction of DM rats and DM patients.International journal of clinical and experimental medicine · 2015Article
- The association of genetic markers for type 2 diabetes with prediabetic status - cross-sectional data of a diabetes prevention trial.PloS one · 2013Article
- Weight status of the first-degree relatives of patients with type 2 diabetes based on the glucose tolerance test.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012Article
- HbA(1c) values for defining diabetes and impaired fasting glucose in Asian Indians.Primary care diabetes · 2011Article
- Normal fasting plasma glucose and risk of prediabetes and type 2 diabetes: the Isfahan Diabetes Prevention Study.The review of diabetic studies : RDS · 2011Article
- Low Levels of High-Density Lipoprotein Cholesterol Do Not Predict the Incidence of Type 2 Diabetes in an Iranian High-Risk Population: The Isfahan Diabetes Prevention Study.The review of diabetic studies : RDSArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to compare the ability of fasting plasma glucose (FPG), post-load plasma glucose values and glycated hemoglobin (HbA1c) to predict progression to diabetes in non-diabetic first-degree relatives (FDR) of patients with type 2 diabetes.
methodsA total of 701 non-diabetic FDR of diabetic patients aged 20-70 years surveyed in 2003 to 2005 were followed until 2008 for the onset of type 2 diabetes mellitus. At baseline and at follow-ups, participants underwent a standard 75 g 2-hour oral glucose tolerance test (OGTT). Prediction of progression to type 2 diabetes was assessed by using area under the receiver-operating characteristic (ROC) curves based upon measurement of FPG, post-load glucose values and HbA1c.
resultsThe incidence of type 2 diabetes was 33.9 per 1000 person-years in men and 48.6 in women. The incidence rates were 4.6, 50.7, and 99.7 per 1000 person-years in FDR with normal glucose tolerance, impaired fasting glucose and impaired glucose tolerance respectively. FPG value was a better predictor of progression to diabetes than any post-load glucose values or HbA1c. The areas under the ROC curves were 0.811 for fasting, 0.752 for 1/2-hour, 0.782 for 1-hour and 0.756 for 2-hour glucose vs. 0.634 for HbA1c (p < 0.001).
conclusionsFPG had more discriminatory power to distinguish between individuals at risk for diabetes and those who were not at risk than post-load glucose values during OGTT or HbA1c. Our findings support the American Diabetes Association recommendation of using FPG concentration to diagnose diabetes.
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