Evidence map›Paper›PMID 19806070›Full record

ArticleJournal of public health policy2009

Factors associated with serum retinol, alpha-tocopherol, carotenoids, and selenium in Hispanics with problems of HIV, chronic hepatitis C, and drug use.

Janet E Forrester, Xiang D Wang, Tamsin A Knox, Carmia G Borek, Alice M Tang, Elizabeth J Johnson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of public health policy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Selenium deficiency and pregnancy outcome in pregnant women with HIV in Lagos, Nigeria.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2018
    Article
  5. Review
  6. Role of vitamins in gastrointestinal diseases.World journal of gastroenterology · 2015
    Review
  7. Article
  8. Article
  9. Selenium deficiency and HIV infection.Infectious disease reports · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Janet E ForresterTufts University School of Medicine, Boston, MA, US. janet.forrester@tufts.edu
Xiang D Wang
Tamsin A Knox
Carmia G Borek
Alice M Tang
Elizabeth J Johnson
Tufts University · US

Funding

ZIDOVUDINE &LAMIVUDINE ALONE OR IN COMBINATION ON BODY COMPOSITIONM01RR000054 · NCRR · TUFTS MEDICAL CENTER · PI RAO, MADHUMATHI · 1985 to 2005
$12.2M
Nutrition and Metabolism CoreP30DA013868 · NIDA · TUFTS UNIVERSITY BOSTON · PI WANKE, CHRISTINE A · 2002 to 2012
$10.0M
NUTRITION FOR LIFE COHORTP01DK045734 · NIDDK · TUFTS UNIVERSITY BOSTON · PI GORBACH, SHERWOOD · 1994 to 2004
$6.6M
NUTRITIONAL STATUS IN HIV POSITIVE HISPANIC DRUG ABUSERSR01DA011598 · NIDA · TUFTS UNIVERSITY BOSTON · PI FORRESTER, JANET E · 1999 to 2008
$5.9M
Micronutrient Metabolism in HIV+and HIV-Drug UsersR01DA014501 · NIDA · TUFTS UNIVERSITY BOSTON · PI FORRESTER, JANET E · 2002 to 2004
$1.2M
NCRR NIH HHS M01 RR000054NCRR NIH HHS M0I-RR00054NIDA NIH HHS DA 11598NIDA NIH HHS DA14501NIDA NIH HHS P30 DA013868NIDA NIH HHS R01 DA011598NIDA NIH HHS R01 DA014501NIDDK NIH HHS DK4 5734-07NIDDK NIH HHS P01 DK045734PHS HHS P308I42853
6 · The paper itself

Abstract

The effects of hepatitis and drug use on nutritional problems in HIV infection have rarely been examined despite the importance of drug use in the global HIV pandemic. We examined the effects of HIV, hepatitis C, and drug use on serum micronutrients in 300 US Hispanic adults. Chronic hepatitis C infection was associated with lower serum retinol (-8.2 microg/dl, P < 0.0001), alpha-tocopherol (-0.10 ln microg/dl, P = 0.024), and carotenoids (-19.8 microg/dl, P < 0.0001). HIV infection was associated with lower selenium (-6.1 microg/l, P = 0.028). Elevated triglycerides in HIV infection were associated with higher serum retinol and alpha-tocopherol. Drug use was not independently associated with micronutrient alterations. We conclude that hepatitis C is an important determinant of low serum micronutrients, and should be considered in any nutritional assessment of HIV infected populations. As the safety of micronutrient supplementation is not established, policy for appropriate HIV clinical care should distinguish between populations with and without hepatitis coinfection.

Indexed as

Hispanic or LatinoAdultalpha-TocopherolCarotenoidsCohort StudiesFemaleHepatitis C, ChronicHIV InfectionsHumansMaleMiddle AgedSeleniumSubstance-Related DisordersUnited StatesVitamin Aalpha-TocopherolCarotenoidsSeleniumVitamin A

Identifiers

PMID19806070
PMCPMC2764270
OpenAlexW2056698638

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.