ArticleProceedings of the National Academy of Sciences of the United States of America2009
Fine-scale mergers of chloroplast and mitochondrial genes create functional, transcompartmentally chimeric mitochondrial genes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- A Systematic Review and Developmental Perspective on Origin of CMS Genes in Crops.International journal of molecular sciences · 2024Pooled it
- Mitochondrial genome characterization and new insights on phylogenetic relationship of Chara (Charophyceae, Charophyta).BMC genomics · 2026Article
- Assembly and comparative analysis of the first complete mitochondrial genome of Camellia sinensis var. assamica 'Hainan Dayezhong', endemic to Hainan Province, China.BMC plant biology · 2025Article
- Article
- The complete mitochondrial genome and phylogenetic analysis ofFrontiers in plant science · 2025Article
- De Novo Hybrid Assembly Unveils Multi-Chromosomal Mitochondrial Genomes inInternational journal of molecular sciences · 2024Article
- Article
- Mitochondrial genome variation and intergenomic sequence transfers inFrontiers in plant science · 2024Article
- Phylogenomics and topological conflicts in the tribe Anthospermeae (Rubiaceae).Ecology and evolution · 2024Article
- Sequencing and analysis of the complete mitochondrial genomes of Toona sinensis and Toona ciliata reveal evolutionary features of Toona.BMC genomics · 2023Article
- Comparative analysis of mitochondrial genomes of two alpine medicinal plants of Gentiana (Gentianaceae).PloS one · 2023Article
- Comparative analysis of mitochondrial genomes ofFrontiers in plant science · 2023Article
- Comparative analysis of mitochondrial genomes reveals marine adaptation in seagrasses.BMC genomics · 2022Article
- The Complete Mitochondrial Genome ofGenes · 2022Article
- Horizontal Gene Transfer Involving Chloroplasts.International journal of molecular sciences · 2021Review
- Evidence of mitochondrial DNA in the chloroplast genome of Convallaria keiskei and its subsequent evolution in the Asparagales.Scientific reports · 2019Article
- Towards a comprehensive picture of C-to-U RNA editing sites in angiosperm mitochondria.Plant molecular biology · 2018Article
- Intercompartmental Piecewise Gene Transfer.Genes · 2017Review
- Mitochondrial Retroprocessing Promoted Functional Transfers of rpl5 to the Nucleus in Grasses.Molecular biology and evolution · 2017Article
- Foreign Plastid Sequences in Plant Mitochondria are Frequently Acquired Via Mitochondrion-to-Mitochondrion Horizontal Transfer.Scientific reports · 2017Article
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2 authors at 1 institution in 1 country.
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Abstract
The mitochondrial genomes of flowering plants possess a promiscuous proclivity for taking up sequences from the chloroplast genome. All characterized chloroplast integrants exist apart from native mitochondrial genes, and only a few, involving chloroplast tRNA genes that have functionally supplanted their mitochondrial counterparts, appear to be of functional consequence. We developed a novel computational approach to search for homologous recombination (gene conversion) in a large number of sequences and applied it to 22 mitochondrial and chloroplast gene pairs, which last shared common ancestry some 2 billion years ago. We found evidence of recurrent conversion of short patches of mitochondrial genes by chloroplast homologs during angiosperm evolution, but no evidence of gene conversion in the opposite direction. All 9 putative conversion events involve the atp1/atpA gene encoding the alpha subunit of ATP synthase, which is unusually well conserved between the 2 organelles and the only shared gene that is widely sequenced across plant mitochondria. Moreover, all conversions were limited to the 2 regions of greatest nucleotide and amino acid conservation of atp1/atpA. These observations probably reflect constraints operating on both the occurrence and fixation of recombination between ancient homologs. These findings indicate that recombination between anciently related sequences is more frequent than previously appreciated and creates functional mitochondrial genes of chimeric origin. These results also have implications for the widespread use of mitochondrial atp1 in phylogeny reconstruction.
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