ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2009
Twins eye study in Tasmania (TEST): rationale and methodology to recruit and examine twins.
Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 7 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Refractive Error Centile Curves for Asian and Western Children and Adolescents: An Individual Level Meta-Analysis.Investigative ophthalmology & visual science · 2025Pooled it
- Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.Nature communications · 2018Pooled it
- Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.Human genetics · 2015Pooled it
- Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.American journal of human genetics · 2013Pooled it
- Genetic loci for retinal arteriolar microcirculation.PloS one · 2013Pooled it
- Genetic variants near PDGFRA are associated with corneal curvature in Australians.Investigative ophthalmology & visual science · 2012Pooled it
- Genome-wide association identifies ATOH7 as a major gene determining human optic disc size.Human molecular genetics · 2010Pooled it
- Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors.Translational vision science & technology · 2023Article
- Observations on Refractive Status and Risk Factors for Visual Impairment in Children with Disabilities.Medicina (Kaunas, Lithuania) · 2021Article
- Genetically low vitamin D concentrations and myopic refractive error: a Mendelian randomization study.International journal of epidemiology · 2017Article
- Retinal microvessels reflect familial vulnerability to psychotic symptoms: A comparison of twins discordant for psychotic symptoms and controls.Schizophrenia research · 2015Article
- Genetic and environmental factors in conjunctival UV autofluorescence.JAMA ophthalmology · 2015Article
- Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.Nature genetics · 2014Article
- Copy number variation at chromosome 5q21.2 is associated with intraocular pressure.Investigative ophthalmology & visual science · 2013Article
- Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.Molecular vision · 2013Article
- GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development.American journal of human genetics · 2011Article
- Ophthalmic phenotypes and the representativeness of twin data for the general population.Investigative ophthalmology & visual science · 2011Article
- Automated quantification of inherited phenotypes from color images: a twin study of the variability of optic nerve head shape.Investigative ophthalmology & visual science · 2010Article
- Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.PLoS genetics · 2010Article
- Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.Nature genetics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 7 institutions in 3 countries.
Funding
Abstract
Visual impairment is a leading cause of morbidity and poor quality of life in our community. Unravelling the mechanisms underpinning important blinding diseases could allow preventative or curative steps to be implemented. Twin siblings provide a unique opportunity in biology to discover genes associated with numerous eye diseases and ocular biometry. Twins are particularly useful for quantitative trait analysis through genome-wide association and linkage studies. Although many studies involving twins rely on twin registries, we present our approach to the Twins Eye Study in Tasmania to provide insight into possible recruitment strategies, expected participation rates and potential examination strategies that can be considered by other researchers for similar studies. Five separate avenues for cohort recruitment were adopted: (1) piggy-backing existing studies where twins had been recruited, (2) utilizing the national twin registry, (3) word-of-mouth and local media publicity, (4) directly approaching schools, and finally (5) collaborating with other research groups studying twins.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.