ReviewJournal of gastroenterology2009
Inflammatory bowel disease: review from the aspect of genetics.
Review in Journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 58 citations in OpenAlex.
- Colon delivery of agomelatine nanoparticles in the treatment of TNBS induced ulcerative colitis.Drug delivery and translational research · 2025Article
- Corrigendum: Inflammatory and Microbiota-Related Regulation of the Intestinal Epithelial Barrier.Frontiers in nutrition · 2021Article
- Inflammatory and Microbiota-Related Regulation of the Intestinal Epithelial Barrier.Frontiers in nutrition · 2021Review
- Toll-Interacting Protein Regulates Immune Cell Infiltration and Promotes Colitis-Associated Cancer.iScience · 2020Article
- A Direct Effect of Sex Hormones on Epithelial Barrier Function in Inflammatory Bowel Disease Models.Cells · 2019Article
- Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression.Frontiers in immunology · 2018Review
- A Potential Role ofFrontiers in immunology · 2017Review
- Article
- The role of B-1 cells in inflammation.Immunologic research · 2015Review
- Inflammatory bowel disease in pediatric and adolescent patients: a biomolecular and histopathological review.World journal of gastroenterology · 2014Article
- Article
- Sirolimus ameliorates inflammatory responses by switching the regulatory T/T helper type 17 profile in murine colitis.Immunology · 2013Article
- Eosinophil associated genes in the inflammatory bowel disease 4 region: correlation to inflammatory bowel disease revealed.World journal of gastroenterology · 2012Article
- Carbohydrate Elimination or Adaptation Diet for Symptoms of Intestinal Discomfort in IBD: Rationales for "Gibsons' Conundrum".International journal of inflammation · 2012Article
- An overview of lipid abnormalities in patients with inflammatory bowel disease.Annals of gastroenterology · 2011Review
- Decreased production of interleukin-10 and transforming growth factor-β in Toll-like receptor-activated intestinal B cells in SAMP1/Yit mice.Immunology · 2010Article
- Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.Clinical and experimental immunology · 2010Article
- Genetics of inflammatory bowel disease in Japan.Journal of gastroenterology · 2010Article
- Inflammatory bowel disease in the dog: differences and similarities with humans.World journal of gastroenterology · 2010Review
- The role of infection in the aetiology of inflammatory bowel disease.Journal of gastroenterology · 2010Review
Corrections and comments
- Commented on by
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regardless of how inflammatory bowel disease (IBD) is defined, the term "genetic susceptibility" is always included. Due to substantial progress in the characterization of susceptible genes that interact with environmental influences, a number of review articles offering the latest insights continue to be presented. To date, more than 30 novel IBD susceptible loci have been found, while several promising associations between IBD and gene variants have also been identified and replicated effectively. The present review highlights recent insights regarding linkage analysis and genome-wide association presented in studies of IBD susceptible genes, which provide additional evidence supporting their involvement in disease pathogenesis, based on linking to innate immune systems as a result of interactions with intestinal microbial flora. An improved understanding of IBD genetics will promote the identification of novel therapeutic agents, making it possible to identify environmental factors related to intestinal inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.