ArticleChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2009
X chromosomal regulation in flies: when less is more.
Article in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Functional Significance of Satellite DNAs: Insights FromFrontiers in cell and developmental biology · 2020Review
- Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells.Nature communications · 2018Article
- NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins.Epigenetics & chromatin · 2017Article
- How do lncRNAs regulate transcription?Science advances · 2017Review
- A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing.The Journal of biological chemistry · 2014Article
- Buffering and proteolysis are induced by segmental monosomy in Drosophila melanogaster.Nucleic acids research · 2012Article
- POF regulates the expression of genes on the fourth chromosome in Drosophila melanogaster by binding to nascent RNA.Molecular and cellular biology · 2012Article
- Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription.Nature reviews. Genetics · 2012Review
- The NSL complex regulates housekeeping genes in Drosophila.PLoS genetics · 2012Article
- Buffering and the evolution of chromosome-wide gene regulation.Chromosoma · 2011Review
- Role of the ATPase/helicase maleless (MLE) in the assembly, targeting, spreading and function of the male-specific lethal (MSL) complex of Drosophila.Epigenetics & chromatin · 2011Article
- Sex-biased transcription enhancement by a 5' tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila.BMC molecular biology · 2010Article
- Nuclear organization and dosage compensation.Cold Spring Harbor perspectives in biology · 2010Review
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Drosophila, dosage compensation of the single male X chromosome involves upregulation of expression of X linked genes. Dosage compensation complex or the male specific lethal (MSL) complex is intimately involved in this regulation. The MSL complex members decorate the male X chromosome by binding on hundreds of sites along the X chromosome. Recent genome wide analysis has brought new light into X chromosomal regulation. It is becoming increasingly clear that although the X chromosome achieves male specific regulation via the MSL complex members, a number of general factors also impinge on this regulation. Future studies integrating these aspects promise to shed more light into this epigenetic phenomenon.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.