ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2010
Blood velocity measurement in the posterior segment of the rabbit eye using combined spectral Doppler and power Doppler ultrasound.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Ultrafast power Doppler imaging for RV myocardial perfusion assessment: histopathologic correlation andEuropean heart journal. Imaging methods and practice · 2026Article
- Super-Resolution Ultrasound Localization Microscopy for Visualization of the Ocular Blood Flow.IEEE transactions on bio-medical engineering · 2022Article
- Ocular surface heat effects on ocular hemodynamics detected by real-time measuring device.International journal of ophthalmology · 2018Article
- Doppler ultrasonography of theOpen veterinary journal · 2017Article
- Microvascular endothelial function and severity of primary open angle glaucoma.Eye (London, England) · 2016Article
- In vivo high-frequency contrast-enhanced ultrasonography of choroidal melanoma in rabbits: imaging features and histopathologic correlations.The British journal of ophthalmology · 2013Article
- Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion.Investigative ophthalmology & visual science · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIt is challenging for the current Doppler imaging to detect blood flow in small retinal vessels. Power Doppler, with its high sensitivity to detect minimal blood flow, can be used with spectral Doppler to measure blood velocity in small vessels of the eye and orbit.
methodsSixteen eyes of twelve normal pigmented rabbits were studied, using a dedicated small animal, high-resolution imaging unit (Vevo 770) and 17.6 MHz ultrasound probe. Spectral Doppler (ISPPA = 67.1 W/cm(2), ISPTA = 483.7 mW/cm(2), MI = 0.5) was combined with power Doppler (ISPPA = 137.7 W/cm(2), ISPTA = 83.1 mW/cm(2), MI = 0.77) to measure the blood velocity over each identified vessel, including the central retinal artery and vein, branch retinal artery and vein, choroidal vein, and the long and short posterior ciliary artery. Three readings from each vessel were averaged to reduce measurement error. Three indices were calculated from the arterial blood velocity readings: the resistive index, the pulsatility index and the A/B ratio.
resultsThe highest arterial blood velocity was measured over the long posterior ciliary artery; peak systolic velocity was 18.29 cm/s and end diastolic velocity was 16.63 cm/s, while the lowest arterial blood velocity was measured over the branch retinal artery; peak systolic velocity was 5.08 cm/s and end diastolic velocity was 3.25 cm/s. On the other hand, the highest venous blood velocity was measured over the choroidal veins (7.0 cm/s), and the lowest venous blood velocity was measured over the branch retinal vein (2.88 cm/s). No statistically significant difference was observed between the nasal and temporal retinal arterial blood velocity. Combining power Doppler with spectral Doppler imaging caused no damage and is a safe technique to measure blood velocity.
conclusionA combination of spectral Doppler and power Doppler ultrasound can be used as a noninvasive and efficient tool for reproducible measurement of the blood velocity in the posterior segment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.