ArticleCurrent opinion in colloid & interface science2008
AFM of biological complexes: what can we learn?
Article in Current opinion in colloid & interface science, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 56 citations in OpenAlex.
- Nanobio Interface Between Proteins and 2D Nanomaterials.ACS applied materials & interfaces · 2023Review
- Few-shot deep learning for AFM force curve characterization of single-molecule interactions.Patterns (New York, N.Y.) · 2023Article
- Localizing Binding Sites on Bioconjugated Hydrogen-Bonded Organic Semiconductors at the Nanoscale.Chemphyschem : a European journal of chemical physics and physical chemistry · 2020Article
- A first order phase transition mechanism underlies protein aggregation in mammalian cells.eLife · 2019Article
- Functional protein nanostructures: a chemical toolbox.Chemical Society reviews · 2018Review
- Biophysical Tools to Study Cellular Mechanotransduction.Bioengineering (Basel, Switzerland) · 2017Review
- AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase Inhibitor.PloS one · 2016Article
- Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers.Journal of visualized experiments : JoVE · 2015Article
- Biophysical Studies on BEX3, the p75NTR-Associated Cell Death Executor, Reveal a High-Order Oligomer with Partially Folded Regions.PloS one · 2015Article
- Harnessing proteasome dynamics and allostery in drug design.Antioxidants & redox signaling · 2014Review
- The cytotoxicity of polycationic iron oxide nanoparticles: common endpoint assays and alternative approaches for improved understanding of cellular response mechanism.Journal of nanobiotechnology · 2012Article
- In situ AFM study of amelogenin assembly and disassembly dynamics on charged surfaces provides insights on matrix protein self-assembly.Journal of the American Chemical Society · 2011Article
- AFM force measurements of the gp120-sCD4 and gp120 or CD4 antigen-antibody interactions.Biochemical and biophysical research communications · 2011Article
- A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel.Structure (London, England : 1993) · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The term "biological complexes" broadly encompasses particles as diverse as multisubunit enzymes, viral capsids, transport cages, molecular nets, ribosomes, nucleosomes, biological membrane components and amyloids. The complexes represent a broad range of stability and composition. Atomic force microscopy offers a wealth of structural and functional data about such assemblies. For this review, we choose to comment on the significance of AFM to study various aspects of biology of selected nonmembrane protein assemblies. Such particles are large enough to reveal many structural details under the AFM probe. Importantly, the specific advantages of the method allow for gathering dynamic information about their formation, stability or allosteric structural changes critical for their function. Some of them have already found their way to nanomedical or nanotechnological applications. Here we present examples of studies where the AFM provided pioneering information about the biology of complexes, and examples of studies where the simplicity of the method is used toward the development of potential diagnostic applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.