ReviewTrends in cell biology2009
Caught in the act: quantifying protein behaviour in living cells.
Review in Trends in cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 57 citations in OpenAlex.
- Benchtop IR Imaging of Live Cells: Monitoring the Total Mass of Biomolecules in Single Cells.Analytical chemistry · 2024Article
- Ferrocene probe-assisted fluorescence quenching of PEI-carbon dots for NO detection and the logic gates based sensing of NO enabled by trimodal detection.Scientific reports · 2024Article
- Spatiotemporal three-dimensional transport dynamics of endocytic cargos and their physical regulations in cells.iScience · 2022Article
- Review
- Homo- and Heteroassociations Drive Activation of ErbB3.Biophysical journal · 2019Article
- Investigating supramolecular systems using Förster resonance energy transfer.Chemical Society reviews · 2018Review
- High-throughput single-cell analysis for the proteomic dynamics study of the yeast osmotic stress response.Scientific reports · 2017Article
- Molecular Diffusion in Plasma Membranes of Primary Lymphocytes Measured by Fluorescence Correlation Spectroscopy.Journal of visualized experiments : JoVE · 2017Article
- Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.Frontiers in physiology · 2017Review
- Quantitative dynamics of VE-cadherin at endothelial cell junctions at a glance: basic requirements and current concepts.Discoveries (Craiova, Romania) · 2016Review
- Photoactivatable fluorescein derivatives caged with a (3-hydroxy-2-naphthalenyl)methyl group.The Journal of organic chemistry · 2014Article
- Mathematical simulation of membrane protein clustering for efficient signal transduction.Annals of biomedical engineering · 2012Review
- Improved spatial direct method with gradient-based diffusion to retain full diffusive fluctuations.The Journal of chemical physics · 2012Article
- Regulation from within: the cytoskeleton in transmembrane signaling.Trends in cell biology · 2012Review
- Insights into cell membrane microdomain organization from live cell single particle tracking of the IgE high affinity receptor FcϵRI of mast cells.Bulletin of mathematical biology · 2012Article
- Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.Microbiology and molecular biology reviews : MMBR · 2012Review
- Convenient and rapid removal of detergent from glycolipids in detergent-resistant membrane microdomains.Journal of lipid research · 2012Article
- Nanoscale membrane organization: where biochemistry meets advanced microscopy.ACS chemical biology · 2012Review
- Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy.Biophysical journal · 2011Article
- Single cell analysis of ligand binding and complex formation of interleukin-4 receptor subunits.Biophysical journal · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Protein localization and dynamics both have important roles in cell signal transduction. Biochemical studies have elucidated many details about the chain of events in signal cascades, but the poor temporal resolution and absence of spatial localization in these conventional techniques make it difficult to determine the "where and when" of protein interactions. Over the past decade, imaging technologies and biological tools have developed to a point where many fundamental questions about protein activity can be addressed at the molecular level in living cells, revealing spatio-temporal information that is not provided by traditional biochemical assays. In this review, we illustrate the power of emerging fluorescence microscopy techniques to capture and quantify protein dynamics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.