Evidence map›Paper›PMID 19800473›Full record

ReviewAnalytica chimica acta2009

Review: Microfluidic applications in metabolomics and metabolic profiling.

James R Kraly, Ryan E Holcomb, Qian Guan, Charles S Henry

Abstract readReview
In one paragraph

Review in Analytica chimica acta, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Animal-Free Chemical Safety Assessment.Frontiers in pharmacology · 2016
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James R KralyDepartment of Chemistry, Colorado State University, Fort Collins, Colorado, CO 80523, United States.
Ryan E Holcomb
Qian Guan
Charles S Henry

Funding

Rapid Metabolomic Screening by Microchip CD-ECDR01EB004876 · NIBIB · COLORADO STATE UNIVERSITY · PI HENRY, CHARLES S · 2006 to 2008
$586k
NIBIB NIH HHS R01 EB004876
6 · The paper itself

Abstract

Metabolomics is an emerging area of research focused on measuring small molecules in biological samples. There are a number of different types of metabolomics, ranging from global profiling of all metabolites in a single sample to measurement of a selected group of analytes. Microfluidics and related technologies have been used in this research area with good success. The aim of this review article is to summarize the use of microfluidics in metabolomics. Direct application of microfluidics to the determination of small molecules is covered first. Next, important sample preparation methods developed for microfluidics and applicable to metabolomics are covered. Finally, a summary of metabolomic work as it relates to analysis of cellular events using microfluidics is covered.

Indexed as

MetabolomeElectrophoresis, CapillaryImmunoassayLuminescent MeasurementsMetabolomicsMicrochip Analytical ProceduresMicrofluidicsSpectrophotometry, UltravioletToxicity Tests

Identifiers

PMID19800473
PMCPMC2791705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.