ReviewReviews in endocrine & metabolic disorders2009
Role of biological rhythms in gastrointestinal health and disease.
Review in Reviews in endocrine & metabolic disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 87 citations in OpenAlex.
- Beyond Chronic Stress: Daily Stress Is Associated With Symptoms in Irritable Bowel Syndrome.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026Article
- The role of cryptochrome (CRY) in cancer: molecular mechanisms and clock-based therapeutic strategies.Acta biochimica et biophysica Sinica · 2025Review
- Poor Sleep Quality as a Risk Factor for Constipation Among Community-Dwelling Older Adults in Japan.Cureus · 2023Article
- Peripheral blood lipid and liver and kidney function test results in long-term night shift nurses: a cross-sectional study in South China.Frontiers in endocrinology · 2023Article
- Histone Deacetylase Inhibition by Gut Microbe-Generated Short-Chain Fatty Acids Entrains Intestinal Epithelial Circadian Rhythms.Gastroenterology · 2022Article
- The effects of Levilactobacillus brevis on the physiological parameters and gut microbiota composition of rats subjected to desynchronosis.Microbial cell factories · 2021Article
- Circadian clocks in the digestive system.Nature reviews. Gastroenterology & hepatology · 2021Review
- Environmental factors associated with biological use and surgery in inflammatory bowel disease.Journal of gastroenterology and hepatology · 2021Article
- Lifestyle, psychological stress, and incidence of adolescent constipation: results from the Toyama birth cohort study.BMC public health · 2021Article
- Circadian misalignment by environmental light/dark shifting causes circadian disruption in colon.PloS one · 2021Article
- Altered sleep quality is associated with Crohn's disease activity: an actimetry study.Sleep & breathing = Schlaf & Atmung · 2020Observational
- Several biological benefits of the low color temperature light-emitting diodes based normal indoor lighting source.Scientific reports · 2019Article
- Circadian rhythms: a regulator of gastrointestinal health and dysfunction.Expert review of gastroenterology & hepatology · 2019Review
- Effect of Irritable Bowel Syndrome on Sleep Quality and Quality of Life of Inflammatory Bowel Disease in Clinical Remission.International journal of preventive medicine · 2019Article
- Multilevel Interactions of Stress and Circadian System: Implications for Traumatic Stress.Frontiers in psychiatry · 2019Review
- H. pylori infection induced BMAL1 expression and rhythm disorder aggravate gastric inflammation.EBioMedicine · 2019Article
- Chronotype, social jet lag, sleep debt and food timing in inflammatory bowel disease.Sleep medicine · 2018Article
- Sleep Disturbances Can Be Prospectively Observed in Patients with an Inactive Inflammatory Bowel Disease.Digestive diseases and sciences · 2018Article
- Fatigued Patients with Chronic Liver Disease Have Subtle Aberrations of Sleep, Melatonin and Cortisol Circadian Rhythms.Fatigue : biomedicine, health & behavior · 2018Article
- Effects of Psychological, Environmental and Physical Stressors on the Gut Microbiota.Frontiers in microbiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The molecular basis for biological rhythms is formed by clock genes. Clock genes are functional in the liver, within gastrointestinal epithelial cells and neurons of the enteric nervous system. These observations suggest a possible role for clock genes in various circadian functions of the liver and the gastrointestinal tract through the modulation of organ specific clock-controlled genes. Consequently, disruptions in circadian rhythmicity may lead to adverse health consequences. This review will focus on the current understanding of the role of circadian rhythms in the pathogenesis of gastrointestinal- and hepatic disease such as obesity, non-alcoholic fatty liver disease, alcoholic fatty liver disease and alterations in colonic motility.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.