ArticleClinical oral investigations2010
Biomonitoring of oral epithelial cells in smokers and non-smokers submitted to panoramic X-ray: comparison between buccal mucosa and lateral border of the tongue.
Article in Clinical oral investigations, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Does smoking habit increase the micronuclei frequency in the oral mucosa of adults compared to non-smokers? A systematic review and meta-analysis.Clinical oral investigations · 2018Pooled it
- Impact of cigarette smoking on genetic stability, cell division, and cytotoxicity in buccal cells of old and young women.Mutagenesis · 2026Article
- What are the Criteria and Conditions for Performing the Micronucleus Assay in Oral Exfoliated Cells from Waterpipe and Cigarette Smokers?International journal of preventive medicine · 2023Article
- Radiobiological risks following dentomaxillofacial imaging: should we be concerned?Dento maxillo facial radiology · 2021Review
- Re: Does smoking habit increase the micronuclei frequency in the oral mucosa of adults compared to non-smokers? A systematic review and meta-analysis. de Geus et al., Clin Oral Investig. 2018 Jan; 22(1):81-91.Clinical oral investigations · 2019Article
- Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures.Environmental health : a global access science source · 2017Article
- Genotoxic effects of X-rays in buccal mucosal cells in children subjected to dental radiographs.BDJ open · 2016Article
- Cytogenetic biomonitoring of oral mucosa cells of crack cocaine users.Environmental science and pollution research international · 2014Article
- Mutagenicity and cytotoxicity in patients submitted to ionizing radiation.The Angle orthodontist · 2013Article
- Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning.The Angle orthodontist · 2012Article
- Cytogenetic biomonitoring in oral mucosa cells following dental X-ray.Dento maxillo facial radiology · 2012Review
- GENOTOXICITY AND CYTOTOXICITY OF X-RAYS IN CHILDREN EXPOSED TO PANORAMIC RADIOGRAPHY.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao PauloArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to comparatively evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated oral mucosa cells from smokers and non-smokers submitted to dental X-ray using two anatomic sites: buccal mucosa and lateral border of the tongue. A total of 15 heavy smokers and 17 non-smokers were submitted to panoramic dental radiography for orthodontic reasons. Individuals had epithelial cells from cheek and lateral border of the tongue mechanically exfoliated, placed in fixative, and dropped in clean slides which were checked for the above nuclear phenotypes. The results pointed out no significant statistically differences (p > 0.05) of micronucleated oral mucosa cells before versus after X-ray exposure for both oral sites evaluated either to smokers or to non-smokers. X-ray exposure was able to increase other nuclear alterations closely related to cytotoxicity such as karrhyorexis, pyknosis, and karyolysis for two groups evaluated. Nevertheless, the most pronunciated effects were found to lateral border of the tongue of smokers. In summary, these data indicate that panoramic X-ray is able to induce cellular death in oral mucosa cells. It seems that lateral border of the tongue is more sensitive site to cytotoxic insult induced by ionizing radiation combined with continuous cigarette smoke exposure.
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