ReviewJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2010
Regulation of copper transport in Arabidopsis thaliana: a biochemical oscillator?
Review in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 105 citations in OpenAlex.
- Bioinformatic study of copper-associated proteins of bread wheat.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Transcriptomic analysis reveals role of lncRNA LOC100257036 to regulate AGAMOUS during cluster compactness of Vitis vinifera cv. sistan yaghooti.Scientific reports · 2024Article
- SOS1 gene family in mangrove (Kandelia obovata): Genome-wide identification, characterization, and expression analyses under salt and copper stress.BMC plant biology · 2024Article
- Biofortification of Triticum species: a stepping stone to combat malnutrition.BMC plant biology · 2024Review
- Distinct function of Chlamydomonas CTRA-CTR transporters in Cu assimilation and intracellular mobilization.Metallomics : integrated biometal science · 2024Article
- Genome-Wide Identification, Characterization, and Expression Analysis of the Copper-Containing Amine Oxidase Gene Family in MangroveInternational journal of molecular sciences · 2023Review
- Genome-Wide Identification and Expression Analysis of the Copper Transporter (International journal of molecular sciences · 2023Review
- Molecular Responses of Red Ripe Tomato Fruit to Copper Deficiency Stress.Plants (Basel, Switzerland) · 2023Article
- Effect of Light Quality on Metabolomic, Ionomic, and Transcriptomic Profiles in Tomato Fruit.International journal of molecular sciences · 2022Article
- The Design of Experiment as a Tool to Model Plant Trace-Metal Bioindication Abilities.Molecules (Basel, Switzerland) · 2022Article
- Multi-Modal Regulation of Circadian Physiology by Interactive Features of Biological Clocks.Biology · 2021Review
- Production of Antioxidant Molecules inInternational journal of molecular sciences · 2020Article
- The Geomagnetic Field Is a Contributing Factor for an Efficient Iron Uptake inFrontiers in plant science · 2020Article
- Article
- Growth, physiological responses, and copper accumulation in seven willow species exposed to Cu-a hydroponic experiment.Environmental science and pollution research international · 2018Article
- Expression of the Intracellular COPT3-Mediated Cu Transport Is Temporally Regulated by the TCP16 Transcription Factor.Frontiers in plant science · 2018Article
- Identification and functional characterization of the ZmCOPT copper transporter family in maize.PloS one · 2018Article
- COPT2, a plasma membrane located copper transporter, is involved in the uptake of Au in Arabidopsis.Scientific reports · 2017Article
- Responses of Plant Proteins to Heavy Metal Stress-A Review.Frontiers in plant science · 2017Review
- Genetically Programmed Changes in Photosynthetic Cofactor Metabolism in Copper-deficient Chlamydomonas.The Journal of biological chemistry · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants are among the most versatile higher eukaryotes in accommodating environmental copper availability to largely variable demands. In particular, copper deficiency in soils is a threat for plant survival since it mostly affects reproductive structures. One of the strategies that plant cells use to overcome this situation is to increase copper levels by expressing high-affinity copper transporters delivering the metal to the cytosol. In this minireview, we discuss recent advances in the structure, function, and regulation of the CTR/COPT family of copper transporters, and pay special attention to the Arabidopsis thaliana counterparts. These are constituted by transmembrane polypeptides, containing several copper-binding sequences of functional and/or regulatory value, and assembling as trimers. Copper deficiency activates the expression of some members of the COPT family via the interaction of the SPL7 transcription factor with reiterative GTAC motifs present in their promoters. Interestingly, the regulation of the synthesis of these transporters by copper itself constitutes a negative-feedback loop that could cause a sustained oscillation in the cytosolic copper levels. We analyze the theoretical conditions required for this hypothetical copper oscillation and the potential advantages of synchronization with other cycles. Diverse data in other organisms point to the relationship between copper homeostasis and circadian cycles.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.