Trial reportEuropean journal of clinical pharmacology2009
Nurse-led medication reviews and the quality of drug treatment of elderly hospitalized patients.
Trial report in European journal of clinical pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Assessing the Effectiveness of Interventions Implemented by Nurses to Reduce Medication Administration Errors in Hospitalised Acute Adult Patient Settings: Systematic Review and Meta-Analysis.Journal of clinical nursing · 2026Pooled it
- A systematic review of the outcomes reported in trials of medication review in older patients: the need for a core outcome set.British journal of clinical pharmacology · 2017Pooled it
- A systematic review of educational interventions to change behaviour of prescribers in hospital settings, with a particular emphasis on new prescribers.British journal of clinical pharmacology · 2013Pooled it
- Impact of collaborative pharmaceutical care on older inpatients' medication safety: multicentre stepped-wedge cluster randomised trial (MEDREV Study).BMC geriatrics · 2025Trial
- Impact of nurse-led home visits on medication management and use of medical screenings for adults with intellectual disabilities: a randomised-controlled trial.BMC nursing · 2026Article
- District nurses' experiences of using a clinical decision support system and an assessment tool at elderly care units in primary health care: a qualitative study.Primary health care research & development · 2021Article
- The NUPHAC-EU Framework for Nurses' Role in Interprofessional Pharmaceutical Care: Cross-Sectional Evaluation in Europe.International journal of environmental research and public health · 2021Article
- Home Care Patients' Experiences with Home Care Nurses' Support in Medication Adherence.Patient preference and adherence · 2021Article
- District nurses' use of a decision support and assessment tool to improve the quality and safety of medication use in older adults: a feasibility study.Primary health care research & development · 2020Article
- Article
- Investigating the Relative Significance of Drug-Related Problem Categories.Pharmacy (Basel, Switzerland) · 2017Review
- A comparison of estimated drug costs of potentially inappropriate medications between older patients receiving nurse home visit services and patients receiving pharmacist home visit services: a cross-sectional and propensity score analysis.BMC health services research · 2015Article
- Application of drug-related problem (DRP) classification systems: a review of the literature.European journal of clinical pharmacology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate if nurses after receiving training in clinical pharmacology can improve the quality of the drug therapy in elderly hospitalized patients.
methodsNurses were given a 1-day training in clinical pharmacology to identify drug-related problems (DRPs).All patients admitted to the ward aged 65 or more were studied. Patients at the same ward before the intervention were considered as control group. Outcome variables were re-hospitalized 3 months from discharge, drug-related readmissions, the proportion of inappropriate drug use (IDU), and DRPs found by the nurses.
resultsOf 460 patients (250 intervention group and 210 in the control group) 38 and 36%, respectively, had at least one re-admission to hospital (p=0.86) and 24% of the patients died. Eighteen and 17% (43/37), respectively, used one or more inappropriate drug (p 0.90). The nurses found 86 clinically significant DRPs not detected by the usual care. A substantial part of the DRPs detected by the nurses were revealed with assistance of Symptoms Assessment Form (SYM). There were no statistical difference in the number of drug-related re-admissions between the groups, 14/16, respectively, (p=0.40).
conclusionsNurses are able to detect a high proportion of clinically relevant DRPs not detected by the usual care and thereby increase the quality of the drug treatment in elderly hospitalized patients. Our study showed no effect on re-hospitalization or IDU. By using a SYM nurses can find DRPs that computer-based decision support systems miss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.