ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2010
Predictors of oral bisphosphonate prescriptions in post-menopausal women with osteoporosis in a real-world setting in the USA.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictors of Ibandronate Efficacy for the Management of Osteoporosis: A Meta-Regression Analysis.PloS one · 2016Pooled it
- Adherence to anti-osteoporosis medication associated with lower mortality following hip fracture in older adults: a nationwide propensity score-matched cohort study.BMC geriatrics · 2019Article
- Examining the treatment gap and risk of subsequent fractures among females with a fragility fracture in the US Medicare population.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Diagnosis and Treatment of Osteoporosis Before and After Fracture: A Side-by-Side Analysis of Commercially Insured and Medicare Advantage Osteoporosis Patients.Journal of managed care & specialty pharmacy · 2017Article
- Association of gastrointestinal events with osteoporosis treatment initiation and treatment compliance in Germany: An observational study.Bone reports · 2016Article
- Patient-reported barriers to osteoporosis therapy.Archives of osteoporosis · 2016Article
- The NYU Osteoporosis Model of Care Experience.Geriatric orthopaedic surgery & rehabilitation · 2015Article
- Association of gastrointestinal events and osteoporosis treatment initiation in newly diagnosed osteoporotic Israeli women.International journal of clinical practice · 2015Article
- Anti-osteoporosis drug prescribing after hip fracture in the UK: 2000-2010.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015Article
- Undertreatment of osteoporosis and the role of gastrointestinal events among elderly osteoporotic women with Medicare Part D drug coverage.Clinical interventions in aging · 2015Article
- A common data model to assess cardiovascular hospitalization and mortality in atrial fibrillation patients using administrative claims and medical records.Clinical epidemiology · 2015Article
- Reasons for not initiating osteoporosis therapy among a managed care population.Patient preference and adherence · 2015Article
- Gastrointestinal events and association with initiation of treatment for osteoporosis.ClinicoEconomics and outcomes research : CEOR · 2015Article
- The association of body mass index with the risk of type 2 diabetes: a case-control study nested in an electronic health records system in the United States.Diabetology & metabolic syndrome · 2014Article
- Hip fracture and other predictors of anti-osteoporosis drug use in Norway.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Article
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- Factors associated with treatment of women with osteoporosis or osteopenia from a national survey.BMC women's health · 2012Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
summaryWe identified factors associated with oral bisphosphonate treatment in 50+-year-old female patients with a first fracture, osteoporosis diagnosis, or BMD < or =-2.5 in the Geisinger Health System electronic health record database. Treatment was positively associated with age, oral corticosteroids, and smoking, and negatively associated with body mass index and bone mineral density scores.
introductionTo identify factors associated with oral bisphosphonate treatment in patients with an indicator for post-menopausal osteoporosis.
methodsFemales age 50+ years with a first fracture, osteoporosis diagnosis, or bone mineral density (BMD) < or =-2.5 (index date) were identified in the Geisinger Health System electronic health record database. Treatment was defined as an oral bisphosphonate prescription order (risedronate sodium, ibandronate sodium, or alendronate) < or =90 days post-index date. Treatment rates were assessed and a multivariate logistic model was used to identify predictors of treatment separately for patients with fracture (FRAC) and with diagnosis or low BMD (ICD-9-BMD).
resultsThe FRAC group had 2,003 female patients with a mean (SD) age of 69.0 (+/-11.3) years and the ICD-9-BMD group had 12,976 female patients with a mean (SD) age of 66.9 (+/-10.0) years. Within 90 days of the index date of fracture, diagnosis, or low BMD score, 188 (9.4%) patients in the FRAC group and 5,395 (41.6%) in the ICD-9-BMD group received treatment. Treatment was positively associated with age and oral corticosteroids and negatively associated with body mass index and subsequent BMD in both groups. Smoking currently was positively associated with treatment in the ICD-9-BMD group.
conclusionCertain patient characteristics are predictors of physicians prescribing oral bisphosphonates. However, many patients remain untreated.
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