SynthesisJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2009
A systematic review of intracranial chondrosarcoma and survival.
Synthesis in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05861245 (Phase II Clinical Trial of Low-intervention Using Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base), which is not on this map. Cited by 61 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase II Clinical Trial of Low-intervention Using Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base
Who cites it
61 citing papers in PubMed, 7 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- CT and MRI findings of intracranial extraskeletal mesenchymal and myxoid chondrosarcoma: report of 3 rare cases and literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Extra-skeletal intracranial mesenchymal chondrosarcoma: systematic-literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Pooled it
- A systematic review and meta-analysis of radiotherapy and particle beam therapy for skull base chondrosarcoma: TRP-chondrosarcoma 2024.Frontiers in oncology · 2024Pooled it
- Efficacy and safety of carbon ion radiotherapy for bone sarcomas: a systematic review and meta-analysis.Radiation oncology (London, England) · 2022Pooled it
- Carbon ion radiotherapy for skull base chordomas and chondrosarcomas: a systematic review and meta-analysis of local control, survival, and toxicity outcomes.Journal of neuro-oncology · 2020Pooled it
- Mesenchymal chondrosarcoma of bone and soft tissue: a systematic review of 107 patients in the past 20 years.PloS one · 2015Pooled it
- Pooled it
- Intracranial Mesenchymal Chondrosarcoma: A Rare Tumor Entity.Annals of neurology · 2026Article
- Sellar chondroma in a pediatric patient treated endoscopically: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Endoscopic transsphenoidal resection of large sellar chondrosarcoma compressing the optic nerve: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Machine learning in automatic detection of chordoma signature, postoperative residuals, and prognosis of skull base chordomas.NPJ precision oncology · 2026Article
- Article
- A 3D navigation-guided surgical resection of a rare case of sacral spine mesenchymal chondrosarcoma: a case report.Journal of spine surgery (Hong Kong) · 2025Article
- The double role of GABAergic system in systemic tumors: an updated review.Frontiers in oncology · 2025Review
- [Clinical analysis of endoscopic transnasal resection of skull base chondrosarcoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024Article
- The Importance of Patient Systemic Health Status in High-Grade Chondrosarcoma Prognosis: A National Multicenter Study.Cancers · 2024Article
- Clival chordomas and chondrosarcomas in Denmark-Outcomes in 33 patients following the national centralization of treatment in 2010.Acta neurochirurgica · 2024Article
- Article
- Skull-Base Chondrosarcoma: A Systematic Review of the Role of Postoperative Radiotherapy.Cancers · 2024Review
- Diagnostics ofDiagnostics (Basel, Switzerland) · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.