Evidence map›Paper›PMID 19796274›Full record

ReviewBritish journal of haematology2009

Alternative haematopoietic stem cell sources for transplantation: place of umbilical cord blood.

Angela R Smith, John E Wagner

Registry-linked trialAbstract readReview
In one paragraph

Review in British journal of haematology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01763099 (Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure Following Autologous Hematopoietic Stem Cell Transplantation), which is not on this map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01763099 phase2unknown statusnot on this mapstarted 2013, after this paper: background citation

Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure Following Autologous Hematopoietic Stem Cell Transplantation

TypeinterventionalSponsorNanfang Hospital, Southern Medical UniversityRan2013 to 2016Enrolled60ConditionsHematopoietic Stem Cell Transplantation, Mesenchymal Stem Cells, Umbilical Cord Blood, Graft FailureArmsMesenchymal stem cells, Mesenchymal stem cells and cord blood
3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Observational
  6. Review
  7. The Evaluation of Mass/DNA Copy Number of Mitochondria in Umbilical Cord Blood-derived Hematopoietic Stem Cells Cocultured with MSCs.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Angela R SmithDivision of Pediatric Hematology/Oncology/Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota Medical School, MMC 484, 420 Delaware Street SE, Minneapolis, MN 55455, USA. smith719@umn.edu
John E Wagner

Funding

Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Mark J Osborn · 1995 to 2026
$48.2M
TRANSPLANT CENTER FOR UMBILICAL CORD STEM CELLN01HB067139 · HB · UNIVERSITY OF MINNESOTA TWIN CITIES · PI WAGNER, JOHN E · 1996 to 2000
$97k
NCI NIH HHS P01 CA065493NCI NIH HHS P0-CA65493NHLBI NIH HHS N01 HB067139NHLBI NIH HHS N01-HB 67139
6 · The paper itself

Abstract

Umbilical cord blood has rapidly become a valuable alternative stem cell source for allogeneic haematopoietic stem cell transplantation. Extensive research over the last 20 years has established the safety and efficacy of umbilical cord blood transplantation in both children and adults with a variety of malignant and non-malignant diseases. This research has clearly shown that this stem cell source has several unique characteristics resulting in distinct advantages and disadvantages when compared to transplantation with unrelated bone marrow or peripheral blood stem cells. This article reviews the most recent literature comparing the outcomes after umbilical cord blood transplantation with other alternative stem cell sources.

Indexed as

AdultChildChild, PreschoolCord Blood Stem Cell TransplantationFanconi AnemiaHematopoietic Stem Cell TransplantationHemoglobinopathiesHumansInfantLeukemiaOpportunistic InfectionsTransplantation Conditioning

Identifiers

PMID19796274
PMCPMC2782564

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.