ReviewXenotransplantation
Current status of xenotransplantation and prospects for clinical application.
Review in Xenotransplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed.
- The xenotransplantation hybrid hospital: structural, economic, and regulatory frameworks for zero-ischemia clinical translation.Clinical transplantation and research · 2026Review
- Liver Xenotransplantation: From Early Primate Trials to the First-in-Human Porcine Bridging Therapies.Journal of clinical medicine · 2026Review
- Developing European policy on xenotransplantation: instructive findings from the first representative UK sample survey on attitudes and views on animal to human transplants.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Xeno kidney: revolutionizing kidney disease treatment.Frontiers in nephrology · 2026Review
- Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation.Cell proliferation · 2025Article
- Surface-Engineering of Pancreatic Islets with Chitosan Microparticles to Inhibit IBMIR in Islet Xenotransplantation.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Moral approval of xenotransplantation in Egypt: associations with religion, attitudes towards animals and demographic factors.BMC medical ethics · 2024Article
- A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34Frontiers in bioengineering and biotechnology · 2024Article
- Regulatory macrophages in solid organ xenotransplantation.Korean journal of transplantation · 2023Review
- Immune characterization of a xenogeneic human lung cross-circulation support system.Science advances · 2023Article
- Orthotopic Heart Auto-Transplantation in a Swine Model.World journal of cardiovascular surgery · 2022Article
- Progress toward Pig-to-Human Xenotransplantation.The New England journal of medicine · 2022Article
- Pig-to-baboon lung xenotransplantation: Extended survival with targeted genetic modifications and pharmacologic treatments.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- Progress in Xenotransplantation: Immunologic Barriers, Advances in Gene Editing, and Successful Tolerance Induction Strategies in Pig-To-Primate Transplantation.Frontiers in immunology · 2022Review
- Constant pH molecular dynamics of porcine circovirus 2 capsid protein reveals a mechanism for capsid assembly.Physical chemistry chemical physics : PCCP · 2021Article
- CRISPR/Cas Technology in Pig-to-Human Xenotransplantation Research.International journal of molecular sciences · 2021Review
- Progress Toward Cardiac Xenotransplantation.Circulation · 2020Review
- Pig-to-human heart transplantation: Who goes first?American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020Article
- Detection of Pig Cells Harboring Porcine Endogenous Retroviruses in Non-Human Primate Bladder After Renal Xenotransplantation.Viruses · 2019Article
- Xenotransplantation: Current Status in Preclinical Research.Frontiers in immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Xenotransplantation is one promising approach to bridge the gap between available human cells, tissues, and organs and the needs of patients with diabetes or end-stage organ failure. Based on recent progress using genetically modified source pigs, improving results with conventional and experimental immunosuppression, and expanded understanding of residual physiologic hurdles, xenotransplantation appears likely to be evaluated in clinical trials in the near future for some select applications. This review offers a comprehensive overview of known mechanisms of xenograft injury, a contemporary assessment of preclinical progress and residual barriers, and our opinions regarding where breakthroughs are likely to occur.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.