ArticleOrganogenesis2009
Design and development of tissue engineered lung: Progress and challenges.
Article in Organogenesis, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 53 citations in OpenAlex.
- Innovative approaches in lung tissue engineering: the role of exosome-loaded bioscaffolds in regenerative medicine.Frontiers in bioengineering and biotechnology · 2024Review
- A Comparative Study of Rat Lung Decellularization by Chemical Detergents for Lung Tissue Engineering.Open access Macedonian journal of medical sciences · 2017Article
- Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ.Respiratory research · 2016Review
- Biomimetic 3D Tissue Models for Advanced High-Throughput Drug Screening.Journal of laboratory automation · 2015Review
- Bioengineering for Organ Transplantation: Progress and Challenges.Bioengineered · 2015Review
- 3D tissue-engineered model of Ewing's sarcoma.Advanced drug delivery reviews · 2014Review
- Engineering de novo assembly of fetal pulmonary organoids.Tissue engineering. Part A · 2014Article
- Adhesion, proliferation, and differentiation of mesenchymal stem cells on RGD nanopatterns of varied nanospacings.Organogenesis · 2013Article
- Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology.Stem cell research & therapy · 2013Review
- Advances in biomimetic regeneration of elastic matrix structures.Drug delivery and translational research · 2012Article
- Comparative molecular developmental aspects of the mammalian- and the avian lungs, and the insectan tracheal system by branching morphogenesis: recent advances and future directions.Frontiers in zoology · 2012Article
- Progress of key strategies in development of electrospun scaffolds: bone tissue.Science and technology of advanced materials · 2012Review
- Human lung cancer cells grown on acellular rat lung matrix create perfusable tumor nodules.The Annals of thoracic surgery · 2012Article
- The reconstruction of lung alveolus-like structure in collagen-matrigel/microcapsules scaffolds in vitro.Journal of cellular and molecular medicine · 2011Article
- Regeneration and orthotopic transplantation of a bioartificial lung.Nature medicine · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Before we can realize our long term goal of engineering lung tissue worthy of clinical applications, advances in the identification and utilization of cell sources, development of standardized procedures for differentiation of cells, production of matrix tailored to meet the needs of the lung and design of methods or techniques of applying the engineered tissues into the injured lung environment will need to occur. Design of better biomaterials with the capacity to guide stem cell behavior and facilitate lung lineage choice as well as seamlessly integrate with living lung tissue will be achieved through advances in the development of decellularized matrices and new understandings related to the influence of extracellular matrix on cell behavior and function. We have strong hopes that recent developments in the engineering of conducting airway from decellularized trachea will lead to similar breakthroughs in the engineering of distal lung components in the future.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.