ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2010
Normal development of brain circuits.
Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02121496 (Social Circumstances, Parenting Techniques, and Infant Development), which is not on this map. Cited by 722 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Social Circumstances, Parenting Techniques, and Infant Development
Who cites it
722 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience.Advanced healthcare materials · 2026Pooled it
- Screen time and attention-deficit/hyperactivity disorder in children: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Pooled it
- Pooled it
- Deep brain stimulation of the hypothalamic region: a systematic review.Acta neurochirurgica · 2025Pooled it
- Executive and attentional functioning interventions in preterm children: a systematic review.Journal of pediatric psychology · 2024Pooled it
- Alcohol and brain structure across the lifespan: A systematic review of large-scale neuroimaging studies.Addiction biology · 2024Pooled it
- Measuring Quantitative Cerebral Blood Flow in Healthy Children: A Systematic Review of Neuroimaging Techniques.Journal of magnetic resonance imaging : JMRI · 2024Pooled it
- Keep the bedtime story: A daily reading ritual improves empathy and creativity in children.PloS one · 2026Trial
- Schizophrenia-associated glycoprotein Adamtsl3 regulates perineuronal net formation, maintenance, and adult cortical plasticity.Molecular psychiatry · 2026Article
- Context-dependent attention and memory outcomes resulting from combined prenatal THC and nicotine exposure following chronic stress.Pharmacology, biochemistry, and behavior · 2026Article
- CLOK: a chemigenetic multicolor labeling system to visualize neuronal birthdate and circuit integration.Nature neuroscience · 2026Article
- Frequency-specific gyro-sulcal functional differentiation in preterm neonates: Sulcal dominance and gene expression correlates.Developmental cognitive neuroscience · 2026Article
- Fetal exposure to persistent organic pollutants and childhood autism risk.Environmental research · 2026Article
- Scale-Dependent Development of Neural Signal Complexity and its Association with Working Memory in Childhood.Brain topography · 2026Article
- Clinical recovery of severe infantileWorld journal of clinical pediatrics · 2026Article
- Hypothalamic c-Fos expression changes during late chicken embryonic development and increases following experimental stimulation.Scientific reports · 2026Article
- Retinal Origins of Aberrant Salience in Schizophrenia: The Perceptual Theory.Biological psychiatry global open science · 2026Review
- Executive Function and Epigenetic Markers in Youth Exposed to Family and Community Violence in Childhood.Developmental psychobiology · 2026Article
- Article
- Spectral organization of individualized connectome harmonics across brain structure, function and cognition.bioRxiv : the preprint server for biology · 2026Article
662 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Spanning functions from the simplest reflex arc to complex cognitive processes, neural circuits have diverse functional roles. In the cerebral cortex, functional domains such as visual processing, attention, memory, and cognitive control rely on the development of distinct yet interconnected sets of anatomically distributed cortical and subcortical regions. The developmental organization of these circuits is a remarkably complex process that is influenced by genetic predispositions, environmental events, and neuroplastic responses to experiential demand that modulates connectivity and communication among neurons, within individual brain regions and circuits, and across neural pathways. Recent advances in neuroimaging and computational neurobiology, together with traditional investigational approaches such as histological studies and cellular and molecular biology, have been invaluable in improving our understanding of these developmental processes in humans in both health and illness. To contextualize the developmental origins of a wide array of neuropsychiatric illnesses, this review describes the development and maturation of neural circuits from the first synapse through critical periods of vulnerability and opportunity to the emergent capacity for cognitive and behavioral regulation, and finally the dynamic interplay across levels of circuit organization and developmental epochs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.