Mutations of NOTCH1, FBXW7, and prognosis in T-lineage acute lymphoblastic leukemia.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

1. The role of the WD40-repeat protein family in cancer.Molecular cancer · 2026
   Review
2. Clinical significance of NOTCH1 and FBXW7 alterations in adult T-cell leukemia/lymphoma.International journal of hematology · 2025
   Article
3. Analysis of 3760 hematologic malignancies reveals rare transcriptomic aberrations of driver genes.Genome medicine · 2024
   Article
4. Isoform alterations in the ubiquitination machinery impacting gastrointestinal malignancies.Cell death & disease · 2024
   Review
5. Targeting P21-activated kinase suppresses proliferation and enhances chemosensitivity in T-cell lymphoblastic lymphoma.Blood science (Baltimore, Md.) · 2023
   Article
6. [The characteristics and prognostic impact of NOTCH1/FBXW7 mutation and CDKN2A/B deletion in adult T-cell acute lymphoblastic leukemia patients].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2021
   Article
7. Preventive Healthcare and Management for Acute Lymphoblastic Leukaemia in Adults: Case Report and Literature Review.Healthcare (Basel, Switzerland) · 2021
   Article
8. Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia.Oncotarget · 2017
   Article
9. Turn It Down a Notch.Frontiers in cell and developmental biology · 2016
   Review
10. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.Haematologica · 2012
    Article
11. Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia.BMC cancer · 2012
    Article

Corrections and comments

• Comment on
  Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia.2009

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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