ArticleJournal of clinical microbiology2009
Efficient diagnosis of vulvovaginal candidiasis by use of a new rapid immunochromatography test.
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 58 citations in OpenAlex.
- The Comparison of vaginal cream of mixing yogurt, honey and clotrimazole on symptoms of vaginal candidiasis.Global journal of health science · 2015Trial
- Vulvovaginal candidiasis among Yemeni women: prevalence of Candida species, biofilm formation rates, antifungal susceptibility patterns, and biofilm-associated genes ALS1 and HWP1.BMC microbiology · 2026Article
- Evaluation of the antifungal efficacy of microbial chondroitin sulfate against candida species in an experimental rat model of vulvovaginal candidiasis.Scientific reports · 2026Article
- Advances in vulvovaginal candidiasis research: a comprehensive review from epidemiology, diagnosis, treatment to resistance mechanisms.Frontiers in microbiology · 2026Review
- Establishment of a latex immunochromatography for detecting bovine early pregnancy-related glycoproteins.Applied microbiology and biotechnology · 2025Article
- Vaginal mycobiome characteristics and therapeutic strategies in vulvovaginal candidiasis (VVC): differentiating pathogenic species and microecological features for stratified treatment.Clinical microbiology reviews · 2025Review
- Phenotypic and Molecular Characterization ofJournal of fungi (Basel, Switzerland) · 2025Article
- The effects of vaginal infections on pregnancy outcomes: a retrospective cohort study in China.BMC pregnancy and childbirth · 2025Article
- Vaginal Royal Jelly for Vulvovaginal Candidiasis Treatment: A Randomized Clinical Trial.Advanced biomedical research · 2025Article
- Antibodies as Models and Tools to DecipherJournal of fungi (Basel, Switzerland) · 2023Review
- Identification and pattern of antifungal susceptibility ofIranian journal of microbiology · 2023Article
- Evaluating the accuracy and diagnostic value of CFW and a new fluorescent reagents, fluorescent brightener 85, for the diagnosis of vulvovaginal candidiasis.Journal of clinical laboratory analysis · 2021Article
- Prevalence of Pathogens and Other Microorganisms in Premenopausal and Postmenopausal Women with Vulvovaginal Symptoms: A Retrospective Study in a Single Institute in South Korea.Medicina (Kaunas, Lithuania) · 2021Review
- Validation of theJournal of fungi (Basel, Switzerland) · 2021Article
- Vaginal microbiota evaluation and prevalence of key pathogens in ecuadorian women: an epidemiologic analysis.Scientific reports · 2020Article
- Vaginal Microbiota Evaluation and Lactobacilli Quantification by qPCR in Pregnant and Non-pregnant Women: A Pilot Study.Frontiers in cellular and infection microbiology · 2020Article
- Comparison of the efficacy of honey gel and clotrimazole cream in the treatment of vaginal candidiasis symptoms: a randomized clinical trial.Electronic physician · 2018Article
- Fungal Profile of Vulvovaginal Candidiasis in a Tertiary Care Hospital.Journal of clinical and diagnostic research : JCDR · 2017Article
- Feasibility of histological scoring and colony count for evaluating infective severity in mouse vaginal candidiasis.Experimental animals · 2013Article
- Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.EMBO molecular medicine · 2012Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical symptoms of vulvovaginal candidiasis (VVC) are nonspecific, and misdiagnosis is common, leading to a delay in the initiation of antifungal treatment. We evaluated a new immunochromatography test (ICT), the CandiVagi assay (SR2B, Avrille, France), for the rapid diagnosis of VVC. This test, which employs an immunoglobulin M antibody directed against the beta-1,2-mannopyranosyl epitopes found in the yeast cell wall, was compared with direct microscopic examination and culture of vaginal swabs. Two-hundred five women were investigated, including 130 women with symptomatic vaginitis and 75 asymptomatic controls. Two vaginal swabs were obtained from each woman: one was used to prepare a wet mount and Gram-stained preparations for direct microscopic examination and was also cultured on Sabouraud dextrose agar for the isolation of Candida spp., and the second swab was used for ICT. The sensitivities of microscopic examination, culture, and ICT for the diagnosis of VVC were 61%, 100%, and 96.6%, respectively, while the specificities of the three methods were 100%, 82%, and 98.6%, respectively. ICT had a negative predictive value of 98.6%, a positive predictive value of 96.6%, and an efficiency of 98%. ICT provided a rapid result and a better compromise between sensitivity and specificity than conventional microscopy and culture for the diagnosis of VVC. This easy-to-perform diagnostic test will be useful to practitioners treating women with symptoms of vaginitis.
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