ArticleThe American journal of clinical nutrition2009
Adipose tissue distribution after weight restoration and weight maintenance in women with anorexia nervosa.
Article in The American journal of clinical nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Body composition in anorexia nervosa: Meta-analysis and meta-regression of cross-sectional and longitudinal studies.The International journal of eating disorders · 2019Pooled it
- Anorexia nervosa and body fat distribution: a systematic review.Nutrients · 2014Pooled it
- Examination of central body fat deposition as a risk factor for loss-of-control eating.The American journal of clinical nutrition · 2015Trial
- Muscle Strength and Functional Performance as Predictors of Metabolic and Body Composition Improvement in Anorexia Nervosa.Nutrients · 2026Article
- Could refeeding-associated gynaecomastia occur during recovery from anorexia nervosa? A hypothesis-generating review.Frontiers in endocrinology · 2026Review
- Resistance training is an underused and promising tool in eating disorder recovery: a narrative review.Journal of eating disorders · 2025Review
- Restoring Weight and Brain Function: Intrinsic Neural Activity and Connectivity Alterations as State Markers of Adolescent Anorexia Nervosa.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Proportion of caloric restriction-induced weight loss as skeletal muscle.Obesity (Silver Spring, Md.) · 2024Article
- Identification of adipose tissue transcriptomic memory of anorexia nervosa.Molecular medicine (Cambridge, Mass.) · 2023Article
- The association between leptin and weight maintenance outcome in anorexia nervosa.The International journal of eating disorders · 2021Article
- Differential glucose metabolism in weight restored women with anorexia nervosa.Psychoneuroendocrinology · 2019Article
- Body composition of children with moderate and severe undernutrition and after treatment: a narrative review.BMC medicine · 2019Review
- Changes in marrow adipose tissue with short-term changes in weight in premenopausal women with anorexia nervosa.European journal of endocrinology · 2019Article
- Review
- Fat Attenuation at CT in Anorexia Nervosa.Radiology · 2016Article
- Segmentation and quantification of adipose tissue by magnetic resonance imaging.Magma (New York, N.Y.) · 2016Review
- Body mass index, body fat and risk factor of relapse in anorexia nervosa.European journal of clinical nutrition · 2016Article
- Daily ingestion of catechin-rich beverage increases brown adipose tissue density and decreases extramyocellular lipids in healthy young women.SpringerPlus · 2016Article
- Follow-up of bone mineral density and body composition in adolescents with restrictive anorexia nervosa: role of dual-energy X-ray absorptiometry.European journal of clinical nutrition · 2014Article
- Article
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Authors and funding
14 authors.
Funding
Abstract
backgroundBody image distortions are a core feature of anorexia nervosa (AN). We, and others, previously reported abnormalities in adipose tissue distribution after acute weight restoration in adult women with AN compared with body mass index-matched healthy control women. Whether these abnormalities persist over time remains unknown.
objectivesWe aimed to 1) replicate previous findings that showed preferential central accumulation of adipose tissue in recently weight-restored AN women compared with control subjects, 2) describe the change within patients with longer-term (1-y) weight maintenance, and 3) compare adipose tissue distribution after 1-y maintenance with that of control subjects.
designBody composition and adipose tissue distribution were assessed by whole-body magnetic resonance imaging in women with AN shortly after weight normalization (n = 30) and again 1 y after hospital discharge (n = 16) and in 8 female control subjects at 2 time points.
resultsWith acute weight restoration, AN patients had significantly greater visceral and intermuscular adipose tissue compared with control women [visceral: 0.75 +/- 0.26 compared with 0.51 +/- 0.26 kg in AN patients and controls, respectively (P = 0.02); intermuscular: 0.46 +/- 0.17 compared with 0.29 +/- 0.13 kg in AN patients and controls, respectively (P = 0.01)]. With maintenance of normal weight for approximately 1 y, visceral adipose tissue distribution in AN patients was not different from that in healthy control subjects.
conclusionsIn adult women with AN, normalization of weight in the short term is associated with a distribution of adipose tissue that is consistent with a central adiposity phenotype. This abnormal distribution appears to normalize within a 1-y period of weight maintenance. This research was registered at clinicaltrials.gov as NCT 00271921 and NCT 00368667.
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