Evidence map›Paper›PMID 19793454›Full record

ReviewComparative medicine2008

Comparative pathobiology of Kaposi sarcoma-associated herpesvirus and related primate rhadinoviruses.

Susan V Westmoreland, Keith G Mansfield

Open access · greenAbstract readReview
In one paragraph

Review in Comparative medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Generation of a specific-pathogen-free baboon colony.Journal of the American Association for Laboratory Animal Science : JAALAS · 2010
    Article
  11. Review
  12. Vaccines to prevent infections by oncoviruses.Annual review of microbiology · 2010
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Susan V WestmorelandHarvard Medical School, New England Primate Research Center, Southborough, MA, USA.
Keith G Mansfield
Harvard University · US

Funding

ZETA CHAIN OF T CELL RECEPTOR INTERACTS W/ NEF OF SIV &HIV2P51RR000168 · NCRR · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WESTMORELAND, SUSAN V. · 1985 to 2011
$139.3M
ESTABLISHMENT OF SPF RHESUS MACAQUE BREEDING COLONY: HIV VACCINE DVMTU42RR016020 · NCRR · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WACHTMAN, LYNN · 2000 to 2011
$5.2M
MOUSE MODELS OF CANCER, BONE DISEASE, AND LACTATIONK26RR000168 · NCRR · OHIO STATE UNIVERSITY · PI ROSOL, THOMAS J · 2000 to 2004
$547k
NCRR NIH HHS K26 RR000168NCRR NIH HHS P51 RR000168NCRR NIH HHS RR00168NCRR NIH HHS RR16020NCRR NIH HHS U42 RR016020
6 · The paper itself

Abstract

With the emergence of the AIDS epidemic over the last 2 decades and the more recent identification of Kaposi sarcoma-associated herpesvirus (KSHV, Human herpesvirus 8), the genera of rhadinoviruses have gained importance as a family of viruses with oncogenic potential. First recognized in New World primates more than 30 y ago, the rhadinoviruses Saimiriine herpesvirus 2 and Ateline herpesvirus 2 have well-described transforming capabilities. Recently several new species-specific rhadinoviruses of Old World primates have been described, including retroperitoneal fibromatosis herpesvirus and rhesus rhadinovirus (Cercopithecine herpesvirus 17). Molecular analysis of these viruses has elucidated several functionally conserved genes and properties shared with KSHV involved in cellular proliferation, transformation, and immune evasion that facilitate the oncogenic potential of these viruses. This review examines the comparative pathobiology of KSHV, discusses the role of macaque rhadinoviruses as models of human disease, and outlines the derivation of specific pathogen-free animals.

Indexed as

AnimalsFemaleHerpes SimplexHerpesvirus 1, CercopithecineHerpesvirus 2, HumanHerpesvirus 8, HumanHumansInfectious Disease Transmission, VerticalInterferon Regulatory Factor-1Interferon Regulatory Factor-4Interferon Regulatory FactorsMicroRNAsOpen Reading FramesPlatyrrhiniPregnancyPrimate DiseasesInterferon Regulatory Factor-1Interferon Regulatory Factor-4Interferon Regulatory FactorsMicroRNAsRNA, ViralViral Proteins

Identifiers

PMID19793454
PMCPMC2703163
OpenAlexW191352206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.