Evidence map›Paper›PMID 19790118›Full record

ArticleArthritis and rheumatism2009

Skeletal health among African Americans with recent-onset rheumatoid arthritis.

J R Curtis, T Arora, M Donaldson, G S Alarcón, L F Callahan, L W Moreland, S L Bridges, T R Mikuls

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthritis and rheumatism, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Challenges of fracture risk assessment in Asian and Black women.The American journal of managed care · 2024
    Article
  2. Article
  3. Article
  4. Stronger bone correlates with African admixture in African-American women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2011
    Article
  5. Article
  6. Bone mineral density changes in patients with recent-onset rheumatoid arthritis.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2011
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

J R CurtisUniversity of Alabama at Birmingham, AL, USA.
T Arora
M Donaldson
G S Alarcón
L F Callahan
L W Moreland
S L Bridges
T R Mikuls
University of Alabama · USUniversity of California, San Francisco · USUniversity of Nebraska Medical Center · USUniversity of North Carolina at Chapel Hill · USUniversity of Pittsburgh · US

Funding

Zevalin Radioimmunotherapy Using a Modified TreatmentM01RR000032 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RICH, ROBERT R. · 1985 to 2008
$23.6M
Sex Related Determinants Of Pain In FibromyalgiaP60AR048095 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI REDDEN, DAVID T · 2002 to 2012
$11.7M
CLEAR-264002247N01AR002247 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2000 to 2004
$805k
Ethnic Differences in the Risk of Fracture and Vascular DiseaseK23AR053351 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CURTIS, JEFFREY R. · 2007 to 2011
$755k
RA Comorbidity Bone Health in Men and African AmericansK23AR050004 · NIAMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MIKULS, TED RICHARD · 2004 to 2008
$498k
Gene-Environment Interactions in RA Autoimmunity and Disease SeverityR03AR054539 · NIAMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MIKULS, TED RICHARD · 2007 to 2009
$218k
NCRR NIH HHS M01 RR000032NIAMS NIH HHS K23 AR050004NIAMS NIH HHS K23 AR053351NIAMS NIH HHS N01 AR002247NIAMS NIH HHS P60 AR048095NIAMS NIH HHS R03 AR054539
6 · The paper itself

Abstract

objectiveAfrican Americans with rheumatoid arthritis (RA) may be at increased fracture risk. We applied the World Health Organization (WHO) Fracture Risk Assessment Tool (FRAX) and National Osteoporosis Foundation (NOF) guidelines to a cohort of African Americans with early RA to identify which patients were recommended for osteoporosis treatment.

methodsRisk factors and bone mineral density (BMD) were assessed in a cohort of African Americans with RA. The WHO FRAX tool estimated 10-year fracture risk. Patients were risk stratified using FRAX without BMD to identify which individuals might be most efficiently targeted for BMD testing.

resultsParticipants (n = 324) had a mean age of 51 years and included 81% women. There were no associations of RA disease characteristics with BMD. The proportion of patients recommended for osteoporosis treatment varied from 3-86%, depending on age and body mass index (BMI). Ten-year fracture risk calculated with BMI only was generally the same or higher than fracture risk calculated with BMD; adding BMD data provided the most incremental value to risk assessment in patients 55-69 years of age with low/normal BMI, and in those > or =70 years of age with BMI > or =30 kg/m2.

conclusionA high proportion of African Americans with RA were recommended for treatment under the 2008 NOF guidelines. FRAX without BMD identified low-risk patients accurately. Systematic application of FRAX to screen high-risk groups such as patients with RA may be used to target individuals for BMD testing and reduce the use of unnecessary tests and treatments.

Indexed as

Black or African AmericanAbsorptiometry, PhotonAdultAgedAged, 80 and overArthritis, RheumatoidBone DensityComorbidityDisability EvaluationFemaleFemur NeckFractures, SpontaneousHealth StatusHumansLumbar VertebraeMale

Identifiers

PMID19790118
PMCPMC2767103
OpenAlexW2115420545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.