Evidence map›Paper›PMID 19789456›Full record

ArticleCritical care medicine2009

Validation of the Infectious Disease Society of America/American Thoracic Society 2007 guidelines for severe community-acquired pneumonia.

Samuel M Brown, Barbara E Jones, Al R Jephson, Nathan C Dean, Infectious Disease Society of America/American Thoracic Society 2007

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in Critical care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02598492 (Imputation of PaO2 From SaO2 in the Respiratory Component of the Sequential Organ Failure Assessment), which is not on this map. Cited by 39 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 5 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02598492 completednot on this mapstarted 2015, after this paper: background citation

Imputation of PaO2 From SaO2 in the Respiratory Component of the Sequential Organ Failure Assessment (SOFA) Score

Typeobservational_patient_registrySponsorBrigham and Women's HospitalRan2015 to 2020Enrolled646ConditionsAcute Respiratory FailureArmsarterial blood gas
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 5 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Guidelines for the management of adult lower respiratory tract infections--full version.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2011
    Guideline
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Deploying an Electronic Clinical Decision Support Tool for Diagnosis and Treatment of Pneumonia Into Rural and Critical Access Hospitals: Utilization, Effect on Processes of Care, and Clinician Satisfaction.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
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  19. Article
  20. Validation of the Pediatric Infectious Diseases Society-Infectious Diseases Society of America Severity Criteria in Children With Community-Acquired Pneumonia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Samuel M BrownDepartment of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. samuel.brown@imail.org
Barbara E Jones
Al R Jephson
Nathan C Dean
Infectious Disease Society of America/American Thoracic Society 2007
University of Utah · US

Funding

UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
Cardiovascular Variability and Control in Early SepsisK23GM094465 · NIGMS · IHC HEALTH SERVICES, INC. · PI BROWN, SAMUEL MORRIS · 2010 to 2014
$637k
NCRR NIH HHS UL1 RR025764NCRR NIH HHS UL1-RR025764NIGMS NIH HHS K23 GM094465
6 · The paper itself

Abstract

objectivesValidate the Infectious Disease Society of America/American Thoracic Society 2007 (IDSA/ATS 2007) criteria for predicting severe community-acquired pneumonia (SCAP) and evaluate a health-services definition for SCAP.

designRetrospective cohort study.

settingLDS Hospital, an academic tertiary care facility in the western United States. PATIENTS: Consecutive patients with International Classification of Diseases, Ninth Edition, codes and chest radiographs consistent with community-acquired pneumonia from 1996 to 2006 seen at LDS Hospital.

interventionsNone. MEASUREMENTS AND MAIN

resultsWe utilized the electronic medical record to examine intensive care unit admission, intensive therapies received, and predictors of severity, as well as 30-day mortality. We also developed logistic regression models of mortality and disease severity. We calculated the IDSA/ATS 2007 criteria as well as three other pneumonia severity scores. We defined SCAP as receipt of intensive therapy in the intensive care unit. In 2413 episodes of pneumonia, 1540 were admitted to the hospital, while 379 were admitted to the intensive care unit. Overall 30-day mortality was 3.7% but was 16% among intensive care patients. The IDSA/ATS 2007 minor criteria predicted SCAP with an area under the curve of 0.88 (95% confidence interval 0.85-0.90), which improved to 0.90 (95% confidence interval 0.88-0.92) with weighting. Competing models had area under the curve of 0.76 to 0.83. Using four rather than three minor criteria improved the positive predictive value from 54% to 81%, with a stable negative predictive value of 94% to 92%.

conclusionsThe IDSA/ATS 2007 criteria predicted pneumonia severity better than other models. Using four rather than three minor criteria may be a superior cutoff, although this will depend on institutional characteristics.

Indexed as

Practice Guidelines as TopicCohort StudiesCommunity-Acquired InfectionsFemaleHumansMaleMiddle AgedPneumonia, BacterialRetrospective StudiesSeverity of Illness Index

Identifiers

PMID19789456
PMCPMC2783880
OpenAlexW2001797310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.