Evidence map›Paper›PMID 19787092›Full record

ArticleGene regulation and systems biology2008

Systems biology and cancer prevention: all options on the table.

Simon Rosenfeld, Izet Kapetanovic

Abstract read
In one paragraph

Article in Gene regulation and systems biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Functional Implications of Cardiac Mitochondria Clustering.Advances in experimental medicine and biology · 2017
    Review
  3. Systems biology for molecular life sciences and its impact in biomedicine.Cellular and molecular life sciences : CMLS · 2013
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Simon RosenfeldDHHS/NIH/National Cancer Institute/Division of Cancer Prevention, EPN, 6130 Executive Blvd, Bethesda, MD 20892, USA. sr212a@nih.gov
Izet Kapetanovic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we outline the status quo and approaches to further development of the systems biology concepts with focus on applications in cancer prevention science. We discuss the biological aspects of cancer research that are of primary importance in cancer prevention, motivations for their mathematical modeling and some recent advances in computational oncology. We also make an attempt to outline in big conceptual terms the contours of future work aimed at creation of large-scale computational and informational infrastructure for using as a routine tool in cancer prevention science and decision making.

Indexed as

biological networkscancer preventiondynamical stabilitygeneral systems theorygenetic regulationmathematical modelingsystems biology

Identifiers

PMID19787092
PMCPMC2733099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.