Evidence map›Paper›PMID 19786203›Full record

ReviewSeminars in hematology2009

Animal models of anemia of inflammation.

Seth Rivera, Tomas Ganz

Abstract readReview
In one paragraph

Review in Seminars in hematology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Biodistribution of intravenous [American journal of nuclear medicine and molecular imaging · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation.Evidence-based complementary and alternative medicine : eCAM · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Seth RiveraDepartment of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA. sethrivera@mednet.ucla.edu
Tomas Ganz

Funding

The role of erythroferrone in iron homeostasis and in iron-loading anemiasR01DK065029 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GANZ, TOMAS · 2004 to 2017
$4.9M
The Link Between Anemia of Inflammation and Host DefenseK08DK074284 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RIVERA, SETH · 2005 to 2009
$610k
NIDDK NIH HHS 1K08DK074284-01NIDDK NIH HHS K08 DK074284
6 · The paper itself

Abstract

Anemia of inflammation (AI) is a complex multi-organ response to inflammatory disorders. Because AI can result from many infectious and non-infectious inflammatory diseases, multiple mechanisms may contribute to its pathogenesis, including iron restriction, direct erythropoietic suppression, shortened red blood cell survival, and frank hemolysis. Animal models have been helpful in the study of the mechanisms of AI and its potential treatments, but each model reflects distinct aspects of this heterogeneous syndrome. It is therefore important to study a variety of models of AI. This review focuses on the use of infectious and noninfectious mouse models of inflammation that have been shown to manifest anemia. We review many of the models reported in the literature or developed in our laboratory, and discuss their respective merits and drawbacks.

Indexed as

Disease Models, AnimalAnemiaAnimalsAntimicrobial Cationic PeptidesBacterial InfectionsHepcidinsInflammationIronMiceMice, TransgenicMycobacterium InfectionsParasitic DiseasesReproducibility of ResultsAntimicrobial Cationic PeptidesHepcidinsIron

Identifiers

PMID19786203
PMCPMC2755601

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.