ReviewCurrent psychiatry reports2009
Gene-environment interactions in attention-deficit/hyperactivity disorder.
Review in Current psychiatry reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 55 citations in OpenAlex.
- Review of rodent models of attention deficit hyperactivity disorder.Neuroscience and biobehavioral reviews · 2022Review
- Mapping relationships between ADHD genetic liability, stressful life events, and ADHD symptoms in healthy adults.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2021Article
- The Interplay Between Prenatal Adversity, Offspring Dopaminergic Genes, and Early Parenting on Toddler Attentional Function.Frontiers in behavioral neuroscience · 2021Article
- Interaction between lead and noradrenergic genotypes affects neurocognitive functions in attention-deficit/hyperactivity disorder: a case control study.BMC psychiatry · 2020Article
- Early sleep deprivation and attention-deficit/hyperactivity disorder.Pediatric research · 2019Article
- How French media have portrayed ADHD to the lay public and to social workers.International journal of qualitative studies on health and well-being · 2017Article
- Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children.Behavioral and brain functions : BBF · 2016Article
- Gene-environment interaction between dopamine receptor D4 7-repeat polymorphism and early maternal sensitivity predicts inattention trajectories across middle childhood.Development and psychopathology · 2013Article
- The genetics of attention deficit/hyperactivity disorder in adults, a review.Molecular psychiatry · 2012Review
- Genetic risks and ADHD symptomatology: exploring the effects of parental antisocial behaviors in an adoption-based study.Child psychiatry and human development · 2012Article
- Why most biomedical findings echoed by newspapers turn out to be false: the case of attention deficit hyperactivity disorder.PloS one · 2012Article
- The dopamine receptor D4 gene (DRD4) moderates family environmental effects on ADHD.Journal of abnormal child psychology · 2011Article
- Why does ADHD confer risk for cigarette smoking? A review of psychosocial mechanisms.Clinical child and family psychology review · 2010Review
- Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults.PloS one · 2010Article
- From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders.European child & adolescent psychiatry · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous disorder characterized by inattention, impulsivity, and/or hyperactivity in children and adults. Putative environmental risk factors for ADHD include toxin and prenatal smoke exposure, low socioeconomic status, and parental marital instability and discord. Genetic associations with ADHD have been found in the dopaminergic, serotonergic, and noradrenergic neurotransmitter systems, but findings are inconsistent across studies. Herein, we review studies of gene-environment interactions for ADHD to better understand how genetic and environmental risk factors may contribute to the disorder in a nonindependent fashion, which may account in part for the inconsistent findings on genetic associations. Although evidence of interactions between prenatal substance exposure and the dopamine genes DAT1 and DRD4 was found, findings across studies have been mixed. We discuss these findings and the future directions and limitations of current gene-environment research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.