ArticleBMC pediatrics2009
Bone and body composition analyzed by Dual-energy X-ray Absorptiometry (DXA) in clinical and nutritional evaluation of young patients with Cystic Fibrosis: a cross-sectional study.
Article in BMC pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Impact of Nutritional Status on Pulmonary Function in Pediatric Cystic Fibrosis: A Retrospective Multicenter Study from Upper Egypt.Medical sciences (Basel, Switzerland) · 2025Article
- Exploring Bone Health in Cystic Fibrosis: A Study From a Lung Transplantation Center and Strategy for Clinical Care.Pediatric pulmonology · 2025Article
- Cystic Fibrosis Bone Disease: The Interplay between CFTR Dysfunction and Chronic Inflammation.Biomolecules · 2023Review
- A growth area: A review of the value of clinical studies of child growth for palaeopathology.Evolution, medicine, and public health · 2022Review
- Triage for Malnutrition Risk among Pediatric and Adolescent Outpatients with Cystic Fibrosis, Using a Disease-Specific Tool.Children (Basel, Switzerland) · 2020Article
- A Survey Identifying Nutritional Needs in a Contemporary Adult Cystic Fibrosis Cohort.BMC nutrition · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
backgroundthe improved general therapy has led to reduced morbidity and mortality from Cystic Fibrosis (CF), and bone status may have a potentially greater clinical impact.We investigated the correlation between the severity of the clinical condition, bone status and body composition parameters, in a group of children and young adults with CF.
methodswe measured lumbar spine bone density and total body composition by dual energy x-ray absorptiometry (DXA) in 82 consecutive CF patients (42 males; median age: 13 years - range: 5-30). Eighty-two healthy subjects, matched for age, gender, height and pubertal stage were recruited as a control group.
results37 patients (45.1%) had a normal bone mineral density (BMD). A BMD reduction were observed in 45 (54.8%) patients. Lumbar spine Z score was positively related to Body Mass Index (BMI) and a higher Shwachman-Kulczycki score, and negatively related to Crispin-Norman score. A positive and significant correlation was also observed between lumbar spine Z score and total body composition.
conclusiona significant BMD reduction can be present early in CF children and adolescents. A careful follow up of bone status is required starting in childhood.
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