Evidence map›Paper›PMID 1978563›Full record

ArticleAmerican journal of human genetics1990

Localization of the human angiogenin gene to chromosome band 14q11, proximal to the T cell receptor alpha/delta locus.

S Weremowicz, E A Fox, C C Morton, B L Vallee

Abstract read
In one paragraph

Article in American journal of human genetics, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Angiogenin for the Diagnosis and Grading of Dry Eye Syndrome.Korean journal of ophthalmology : KJO · 2016
    Article
  4. New insights into the role of angiogenin in actin polymerization.International review of cell and molecular biology · 2012
    Review
  5. Article
  6. Article
  7. Article
  8. Mapping of the neural retina leucine zipper gene, Nrl, to mouse chromosome 14.Mammalian genome : official journal of the International Mammalian Genome Society · 1993
    Article
  9. Mouse chromosome 14.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  10. Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

S WeremowiczCenter for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, Boston, MA.
E A Fox
C C Morton
B L Vallee
Geophysical Laboratory · US

Funding

NHLBI NIH HHS HL-07582
6 · The paper itself

Abstract

The gene encoding angiogenin, a potent inducer of blood vessel formation, has been localized within the human genome. It is present as a single copy per haploid genome and is located on chromosome 14, on the basis of discordancy analysis of human-rodent hybrid cell lines. This localization was refined to 14q11 by in situ hybridization of an angiogenin probe to metaphase chromosomes prepared from both normal human lymphocytes and RPMI 8402 cells. The results from the RPMI 8402 cells also establish that the angiogenin gene resides proximal to a translocation breakpoint within the T cell receptor alpha/delta locus and therefore upstream from that locus. An AvaII RFLP, present at a frequency of 29% in an unselected collection of human placental DNAs, was identified in the coding region of the gene and results from a single silent transversion.

Indexed as

Chromosomes, Human, Pair 14Ribonuclease, PancreaticAngiogenesis Inducing AgentsAnimalsChromosome MappingFemaleGenesGenetic LinkageHaploidyHumansHybrid CellsMaleNucleic Acid HybridizationPolymorphism, Restriction Fragment LengthProteinsReceptors, Antigen, T-CellAngiogenesis Inducing AgentsangiogeninProteinsReceptors, Antigen, T-CellRibonuclease, Pancreatic

Identifiers

PMID1978563
PMCPMC1683891
OpenAlexW2178173864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.