ArticleFoodborne pathogens and disease2010
Contribution of the multidrug efflux transporter CmeABC to antibiotic resistance in different Campylobacter species.
Article in Foodborne pathogens and disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- Infections and Syndromes Caused by Campylobacter.Microorganisms · 2026Review
- Article
- Comparative immunoproteomics ofFrontiers in cellular and infection microbiology · 2026Article
- Pangenomic Characterization ofPathogens (Basel, Switzerland) · 2025Article
- Computational modeling approach to identify potential anti-Campylobacter peptides fromOpen veterinary journal · 2025Review
- Antimicrobial Activity of a Synthetic Brevibacillin Analog Against Multidrug-ResistantInternational journal of molecular sciences · 2025Article
- Genotypic characterization and antimicrobial susceptibility of humanMicrobiology spectrum · 2024Article
- Bacterial Efflux Pump Inhibitors Reduce Antibiotic Resistance.Pharmaceutics · 2024Review
- Infant diarrheal disease in rhesus macaques impedes microbiome maturation and is linked to uncultured Campylobacter species.Communications biology · 2024Article
- Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance Genes and Core-Genome Multilocus Sequence Typing ofInternational journal of molecular sciences · 2023Article
- Comparative genomic analysis ofFrontiers in microbiology · 2023Article
- Genomic and Phenotypic Characterization ofMicroorganisms · 2021Article
- Antimicrobial Resistance Determinants Circulating among ThermophilicAntibiotics (Basel, Switzerland) · 2020Article
- Prevalence, Population Diversity and Antimicrobial Resistance ofMicroorganisms · 2020Article
- Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls.PloS one · 2020Article
- Genomic Analysis Reveals the Genetic Determinants Associated With Antibiotic Resistance in the Zoonotic PathogenFrontiers in microbiology · 2020Article
- Influence of Protein Glycosylation onFrontiers in microbiology · 2020Article
- The Rho-Independent Transcription Terminator for theInfection and immunity · 2019Article
- The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2017.EFSA journal. European Food Safety Authority · 2019Article
- Antimicrobial Resistance inMicrobiology spectrum · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
CmeABC, a multidrug efflux system in Campylobacter jejuni, plays an important role in the resistance to different antimicrobials and toxic compounds. Although this efflux system has been well characterized in C. jejuni and to a less extent in C. coli, it is unknown if CmeABC homologs are functional in other Campylobacter spp. In this study, the cmeABC homologs were identified and functionally characterized in five Campylobacter species including C. jejuni, C. coli, C. lari, C. upsaliensis, and C. fetus. Our results indicated that cmeABC is present in all five Campylobacter spp. and the genomic organization of this efflux operon is similar among the Campylobacter spp. Insertional mutagenesis of cmeB increased the susceptibilities of all the five Campylobacter spp. to structurally diverse antimicrobials. Together, these results indicated that the CmeABC efflux system is conserved at both the genomic and functional levels in all five Campylobacter spp. examined in this study, further highlighting the significant role of CmeABC in Campylobacter pathobiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.