ArticleJournal of clinical laboratory analysis2009
Correlation between Etest, disk diffusion, and microdilution methods for antifungal susceptibility testing of Candida species from infection and colonization.
Article in Journal of clinical laboratory analysis, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Antifungal-induced DNA dynamics and chitin remodelling across Cryptococcus spp. and the novel broad-spectrum anti-cryptococcal candidate CPTH2.Scientific reports · 2026Article
- Mixed oral candidiasis in type 2 diabetic patients: Identification and spectrum of sensitivityBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Raman Spectroscopy of OralInternational journal of molecular sciences · 2022Article
- Uncommon Non-Pathogens (Basel, Switzerland) · 2021Article
- Antifungal profile of vulvovaginal candidiasis in sexually active females from a tertiary care hospital of Western Rajasthan.Journal of family medicine and primary care · 2021Article
- E-test Determination of Antifungal Susceptibility ofJournal of veterinary research · 2020Article
- Application of 2'-OMethylRNA' Antisense Oligomer to Control Candida albicans EFG1 Virulence Determinant.Molecular therapy. Nucleic acids · 2019Article
- Antifungal Drug Susceptibility ofFrontiers in microbiology · 2017Article
- Antifungal Susceptibility Testing with Etest for Candida Species Isolated from Patients with Oral Candidiasis.Annals of dermatology · 2015Article
- Heparin-benzyl alcohol enhancement of biofilms formation and antifungal susceptibility of vaginal Candida species isolated from pregnant and nonpregnant Saudi women.Bioinformation · 2013Article
- Insights into Candida tropicalis nosocomial infections and virulence factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Review
- Susceptibility tests of oropharyngeal Candida albicans from egyptian patients to fluconazole determined by three methods.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2012Article
- Broth microdilution and time-kill testing of Caspofungin, voriconazole, amphotericin B and their combinations against clinical isolates of Candida krusei.Mycopathologia · 2012Article
- In Vitro Susceptibility Testing in Fungi: What is its Role in Clinical Practice?Current infectious disease reports · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The correlation between the microdilution (MD), Etest (ET), and disk diffusion (DD) methods was determined for amphotericin B, itraconazole and fluconazole. The minimal inhibitory concentration (MIC) of those antifungal agents was established for a total of 70 Candida spp. isolates from colonization and infection. The species distribution was: Candida albicans (n=27), C. tropicalis (n=17), C. glabrata (n=16), C. parapsilosis (n=8), and C. lusitaniae (n=2). Non-Candida albicans Candida species showed higher MICs for the three antifungal agents when compared with C. albicans isolates. The overall concordance (based on the MIC value obtained within two dilutions) between the ET and the MD method was 83% for amphotericin B, 63% for itraconazole, and 64% for fluconazole. Considering the breakpoint, the agreement between the DD and MD methods was 71% for itraconazole and 67% for fluconazole. The DD zone diameters are highly reproducible and correlate well with the MD method, making agar-based methods a viable alternative to MD for susceptibility testing. However, data on agar-based tests for itraconazole and amphotericin B are yet scarce. Thus, further research must still be carried out to ensure the standardization to other antifungal agents.
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