Evidence map›Paper›PMID 19784646›Full record

GuidelineEuropean journal of nuclear medicine and molecular imaging2009

Joint practice guidelines for radionuclide lymphoscintigraphy for sentinel node localization in oral/oropharyngeal squamous cell carcinoma.

Lee W T Alkureishi, Zeynep Burak, Julio A Alvarez, James Ballinger, Anders Bilde, Alan J Britten, Luca Calabrese, Carlo Chiesa, Arturo Chiti, Remco de Bree and 19 more

Open access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in European journal of nuclear medicine and molecular imaging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 79 citations in OpenAlex.

  1. Beyond sentinel node biopsy: preliminary results of indocyanine green-guided neck dissection in cN0 tongue cancer.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Article
  2. Review
  3. Review
  4. What is the role of sentinel lymph node biopsy in the management of oral cancer in 2020?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Design and Synthesis ofPharmaceuticals (Basel, Switzerland) · 2018
    Article
  9. Review
  10. Article
  11. Review
  12. Intraoperative 3-D imaging improves sentinel lymph node biopsy in oral cancer.European journal of nuclear medicine and molecular imaging · 2014
    Article
  13. Practice variation in defining sentinel lymph nodes on lymphoscintigrams in oral cancer patients.European journal of nuclear medicine and molecular imaging · 2014
    Article
  14. SPECT/CT and tumour imaging.European journal of nuclear medicine and molecular imaging · 2014
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 20 institutions in 10 countries.

Lee W T AlkureishiDepartment of Plastic Surgery, University of Chicago Medical Center, Chicago, USA. lee_alkureishi@hotmail.com
Zeynep Burak
Julio A Alvarez
James Ballinger
Anders Bilde
Alan J Britten
Luca Calabrese
Carlo Chiesa
Arturo Chiti
Remco de Bree
Harry W Gray
Keith Hunter
Adorjan F Kovacs
Michael Lassmann
C Rene Leemans
Gerard Mamelle
Mark McGurk
Jann Mortensen
Tito Poli
Taimur Shoaib
Philip Sloan
Jens A Sorensen
Sandro J Stoeckli
Jorn B Thomsen
Giusepe Trifiro
Jochen Werner
Gary L Ross
European Association of Nuclear Medicine Oncology Committee
European Sentinel Node Biopsy Trial Committee
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLCopenhagen University Hospital · DKEuropean Institute of Oncology · ITGlasgow Royal Infirmary · GBEge University · TRFondazione IRCCS Istituto Nazionale dei Tumori · ITGoethe University Frankfurt · DEGuy's and St Thomas' NHS Foundation Trust · GBGuy's Hospital · GBInstitut Gustave Roussy · FRIRCCS Humanitas Research Hospital · ITKantonsspital St. Gallen · CHOspedale di Parma · ITPhilipps University of Marburg · DERoyal Victoria Infirmary · GBSt George's Hospital · GBThe Christie Hospital · GBUniversity of Chicago Medical Center · USUniversity of Sheffield · GBUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Involvement of the cervical lymph nodes is the most important prognostic factor for patients with oral/oropharyngeal squamous cell carcinoma (OSCC), and the decision whether to electively treat patients with clinically negative necks remains a controversial topic. Sentinel node biopsy (SNB) provides a minimally invasive method of determining the disease status of the cervical node basin, without the need for a formal neck dissection. This technique potentially improves the accuracy of histological nodal staging and avoids over-treating three-quarters of this patient population, minimizing associated morbidity. The technique has been validated for patients with OSCC, and larger-scale studies are in progress to determine its exact role in the management of this patient population. This article was designed to outline the current best practice guidelines for the provision of SNB in patients with early-stage OSCC, and to provide a framework for the currently evolving recommendations for its use. These guidelines were prepared by a multidisciplinary surgical/nuclear medicine/pathology expert panel under the joint auspices of the European Association of Nuclear Medicine (EANM) Oncology Committee and the Sentinel European Node Trial Committee.

Indexed as

Sentinel Lymph Node BiopsyCarcinoma, Squamous CellHumansLymph NodesMouth NeoplasmsOropharyngeal NeoplasmsRadionuclide Imaging

Identifiers

PMID19784646
PMCPMC2764079
OpenAlexW2162549114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.