Evidence map›Paper›PMID 19781958›Full record

ArticleJournal of the American Society for Mass Spectrometry2009

Cyclization of peptide b9 ions.

Alex G Harrison

Abstract read
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In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Participation of C-H Protons in the Dissociation of a Proton Deficient Dipeptide.Journal of the American Society for Mass Spectrometry · 2017
    Article
  2. Combinatorial Labeling Method for Improving Peptide Fragmentation in Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2017
    Article
  3. Article
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  10. Using gas-phase guest-host chemistry to probe the structures of b ions of peptides.Journal of the American Society for Mass Spectrometry · 2012
    Article
  11. Article
  12. Conformation-specific spectroscopy of peptide fragment ions in a low-temperature ion trap.Journal of the American Society for Mass Spectrometry · 2012
    Article
  13. Article
  14. Article
  15. Structural heterogeneity of doubly-charged peptide b-ions.Journal of the American Society for Mass Spectrometry · 2011
    Article
  16. A systematic study of acidic peptides for b-type sequence scrambling.Journal of the American Society for Mass Spectrometry · 2011
    Article
  17. Article
  18. Effect of the His residue on the cyclization of b ions.Journal of the American Society for Mass Spectrometry · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alex G HarrisonDepartment of Chemistry, University of Toronto, Toronto, ON, Canada. aharriso@chem.utoronto.ca

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The product ion mass spectra obtained by CID of the b(9) ions derived by loss of neutral alanine from the MH+ ion of the peptides Tyr(Ala)9, (Ala)4Tyr(Ala)5, and (Ala)8TyrAla are essentially identical, indicative of full cyclization reaction to a common intermediate before fragmentation. This leads to abundant nondirect sequence ions in the product ion mass spectra of the b9 ions. The product ion mass spectra of the b8 ions from the first two peptides also are essentially identical. The fragmentation of the MH+ ions also leads to low intensity nondirect sequence ions in the product ion mass spectra. N-terminal acetylation blocks the cyclization and eliminates nondirect sequence fragment ions in the product ion mass spectra.

Indexed as

IonsPeptide MappingPeptidesSpectrometry, Mass, Electrospray IonizationIonsPeptides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.