Evidence map›Paper›PMID 19780069›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2009

Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells.

Alex M Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed.

  1. Article
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  15. Article
  16. Review
  17. Article
  18. Core-Shell Nanoparticles for Pulmonary Drug Delivery.Pharmaceutical nanotechnology · 2025
    Review
  19. Article
  20. Review

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alex M ChenDepartment of Chemistry Rutgers, The State of New Jersey, Newark, NJ 07102, USA.
Min Zhang
Dongguang Wei
Dirk Stueber
Oleh Taratula
Tamara Minko
Huixin He

Funding

Targeted Proapoptotic Anticancer Drug Delivery SystemsR01CA100098 · NCI · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI MINKO, TAMARA · 2004 to 2010
$1.9M
Molecular Targeting of Drug Delivery System to CancerR01CA111766 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI MINKO, TAMARA · 2006 to 2010
$1.3M
NCI NIH HHS CA100098NCI NIH HHS CA111766NCI NIH HHS R01 CA100098NCI NIH HHS R01 CA111766
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genes, bcl-2NanoparticlesAntineoplastic AgentsApoptosisCell Line, TumorDoxorubicinDrug Resistance, NeoplasmFemaleHumansMicroscopy, Electron, TransmissionMicroscopy, FluorescenceNanotechnologyOvarian NeoplasmsRNA, Small InterferingSilicon DioxideAntineoplastic AgentsDoxorubicinRNA, Small InterferingSilicon Dioxide

Identifiers

PMID19780069
PMCPMC2833276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.