ReviewNeuroscience and behavioral physiology2009
Origin and molecular evolution of ionotropic glutamate receptors.
Review in Neuroscience and behavioral physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- AMPA receptors in the evolving synapse: structure, function, and disease implications.Frontiers in synaptic neuroscience · 2025Review
- Decoding bee cleptoparasitism through comparative transcriptomics of Coelioxoides waltheriae and its host Tetrapedia diversipes.Scientific reports · 2024Article
- Evolution of glutamatergic signaling and synapses.Neuropharmacology · 2021Review
- In vivo assembly and trafficking of olfactory Ionotropic Receptors.BMC biology · 2019Article
- Coupling of a viral KCommunications biology · 2019Article
- Article
- Genome-wide identification, characterization and classification of ionotropic glutamate receptor genes (iGluRs) in the malaria vector Anopheles sinensis (Diptera: Culicidae).Parasites & vectors · 2018Article
- Identification and Comparison of Chemosensory Genes in the Antennal Transcriptomes ofFrontiers in physiology · 2018Article
- Article
- Alpha1-Adrenoceptor Antagonists Improve Memory by Activating N-methyl-D-Aspartate-Induced Ion Currents in the Rat Hippocampus.International neurourology journal · 2015Article
- Alcohol and NMDA receptor: current research and future direction.Frontiers in molecular neuroscience · 2013Article
- cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells.Cellular and molecular life sciences : CMLS · 2011Article
- Article
- A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence.Nature communications · 2011Article
- Prefrontal cortex and drug abuse vulnerability: translation to prevention and treatment interventions.Brain research reviews · 2011Review
- Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction.PLoS genetics · 2010Article
- Identification of a chemoreceptor for tricarboxylic acid cycle intermediates: differential chemotactic response towards receptor ligands.The Journal of biological chemistry · 2010Article
- Recent surprising similarities between plant cells and neurons.Plant signaling & behavior · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article provides a review of approaches to identification of the pathways of the molecular evolution of glutamate receptors. Extensive evidence has now accumulated on the homology of glutamate-binding proteins with the ability to function as ligand-activated channels. However, knowledge of the amino acid sequences of the polypeptides forming these channels is a necessary but insufficient condition for identifying their origin and changes during evolution. Natural selection of protein molecules appears to have identified and fixed their functional nature. Molecular and functional approaches should therefore complement each other in studies of protein evolution. Studies of glutamate receptor channels in vertebrates and invertebrates provide an example showing how knowledge of the spatial organization and the details of the mechanisms of operation allows relationships to be identified and possible pathways of the molecular evolution of receptors to be established.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.