ArticleAmerican journal of hypertension2009
Aortic pulse pressure is associated with carotid IMT in chronic kidney disease: report from Chronic Renal Insufficiency Cohort.
Article in American journal of hypertension, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT00304148 (Prospective Cohort Study of Chronic Renal Insufficiency), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Cohort Study of Chronic Renal Insufficiency
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants.American journal of hypertension · 2022Pooled it
- Associations between measurements of central blood pressure and target organ damage in high-risk patients.Clinical hypertension · 2021Article
- Cardiovascular End Points and Mortality Are Not Closer Associated With Central Than Peripheral Pulsatile Blood Pressure Components.Hypertension (Dallas, Tex. : 1979) · 2020Article
- Noninvasive central systolic blood pressure, not peripheral systolic blood pressure, independently predicts the progression of carotid intima-media thickness in a Chinese community-based population.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- The Role of Central Blood Pressure Monitoring in the Management of Hypertension.Current cardiology reports · 2018Review
- Role of nebivolol in the control and management of central aortic blood pressure in hypertensive patients.Journal of human hypertension · 2017Review
- Different associations between blood pressure indices and carotid artery damages in a community-based population of China.Journal of human hypertension · 2016Article
- Which Measurement of Blood Pressure Is More Associated With Albuminuria in Patients With Type 2 Diabetes: Central Blood Pressure or Peripheral Blood Pressure?Journal of clinical hypertension (Greenwich, Conn.) · 2016Article
- Decline of Renal Function and Progression of Left Ventricular Hypertrophy Are Independently Determined in Chronic Kidney Disease Stages 3-5.Pulse (Basel, Switzerland) · 2014Article
- Article
- Central pulse pressure in patients with chronic kidney disease and in renal transplant recipients.Journal of human hypertension · 2014Article
- 24-hour central blood pressure and intermediate cardiovascular phenotypes in untreated subjects.American journal of cardiovascular disease · 2014Article
- Evaluation of the EndoPAT as a Tool to Assess Endothelial Function.International journal of vascular medicine · 2012Article
- Non-invasive measurements of atherosclerosis in adult cystinosis patients.Journal of inherited metabolic disease · 2011Article
- Surrogate markers of cardiovascular disease in CKD: what's under the hood?American journal of kidney diseases : the official journal of the National Kidney Foundation · 2011Review
- Chronic Kidney Disease Japan Cohort study: baseline characteristics and factors associated with causative diseases and renal function.Clinical and experimental nephrology · 2010Article
- The Associations of Arterial Stiffness and Central Hemodynamics with Carotid Atherosclerosis in Patients at a High Coronary Risk: A Cross-Sectional Study.Pulse (Basel, Switzerland)Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
13 authors.
Funding
Abstract
backgroundPatients with chronic kidney disease (CKD) have a disproportionate risk of cardiovascular disease. This study was designed to assess the association between two noninvasive measures of cardiovascular risk, pulse wave analysis (PWA), and carotid intima-media thickness (IMT), in a cohort of CKD patients enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study.
methodsThree hundred and sixty-seven subjects with CKD enrolled in the CRIC study at the University of Pennsylvania site (mean age 59.9 years, blood pressure 129/74 mm Hg, estimated glomerular filtration rate 48 ml/min/1.73 m2, IMT 0.8 mm) had both carotid IMT and PWA measurements. Carotid ultrasound was also used to determine the presence of plaque. PWA was used to determine augmentation index (AI), amplification ratio (AMPR), aortic pulse pressure (C_PP), and central aortic systolic pressure (C_SP).
resultsIMT was significantly associated with all PWA-derived measures. However, on multivariable linear regression analysis, only AMPR (regression coefficient -0.072, P = 0.006), C_PP (regression coefficient 0.0025, P < 0.001), and C_SP (regression coefficient 0.0017, P < 0.001) remained significantly associated with IMT. The prevalence of carotid plaque in the cohort was 59%. Of the PWA-derived measures, only C_PP was significantly associated with the presence of carotid plaque (P < 0.001).
conclusionsPWA-derived measures are associated with carotid IMT and plaque in the CKD. Of these measures, C_PP was most associated with carotid IMT and plaque.
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