ReviewCurrent opinion in organ transplantation2009
Stem cells for liver repopulation.
Review in Current opinion in organ transplantation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Novel management of acute or secondary biliary liver conditions using hepatically differentiated human dental pulp cells.Tissue engineering. Part A · 2015Article
- Up-regulation of CXCR4 in rat umbilical mesenchymal stem cells induced by serum from rat with acute liver failure promotes stem cells migration to injured liver tissue.Molecular and cellular biochemistry · 2014Article
- Role of stem cells in repair of liver injury: experimental and clinical benefit of transferred stem cells on liver failure.World journal of gastroenterology · 2013Review
- Successful auto-implantation of hepatic cells in lung tissue: An animal study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013Article
- Human-induced pluripotent stem cells as a source of hepatocyte-like cells: new kids on the block.Hepatology international · 2013Article
- Rodent animal models for surrogate analysis of cell therapy in acute liver failure.Frontiers in physiology · 2012Article
- Enhanced differentiation of adult bone marrow-derived stem cells to liver lineage in aggregate culture.Tissue engineering. Part A · 2011Article
- Anti-fibrogenic strategies and the regression of fibrosis.Best practice & research. Clinical gastroenterology · 2011Review
- From skin cells to hepatocytes: advances in application of iPS cell technology.The Journal of clinical investigation · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purpose of reviewThe capacity of the liver to regenerate and maintain a constant size despite injury is unique. However, the exact mechanisms are not completely clear. Cell transplantation has been proposed as an alternative treatment of liver diseases. Recent progress has been reported on the generation of stem/progenitor cells that may differentiate toward the hepatic lineage. However, it is currently difficult to determine which of the stem/progenitor cell populations are the best for therapy of a given disease. RECENT
findingsThe limited access to donor human hepatocytes has led to a great interest in the generation of hepatocyte-like cells. Several potential cell sources have been identified. However, general standardization of the methods to evaluate these cells is particularly important for the promise of stem/progenitor-derived hepatocyte-based therapies. Moreover, innovations aimed at improving hepatocyte delivery, survival, and engraftment have recently opened the field of organ engineering that may improve liver repopulation. SUMMARY: Here we review current evidence reported from the perspective of potential clinical applications of different hepatic cell sources with repopulation capacities and the future perspectives and tools that can facilitate the translation of laboratory work into clinical success.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.