Evidence map›Paper›PMID 19778848›Full record

ReviewClinical lymphoma & myeloma2009

Never say die: survival signaling in large granular lymphocyte leukemia.

Mithun Vinod Shah, Ranran Zhang, Thomas P Loughran

Open access · greenAbstract readReview
In one paragraph

Review in Clinical lymphoma & myeloma, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Uncovering the significance of expanded CD8Frontiers in immunology · 2023
    Article
  4. Article
  5. Article
  6. Genomics of LGL leukemia and select other rare leukemia/lymphomas.Best practice & research. Clinical haematology · 2019
    Review
  7. Article
  8. Immune aging and autoimmunity.Cellular and molecular life sciences : CMLS · 2012
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mithun Vinod ShahPenn State Hershey Cancer Institute, Hershey, PA, USA.
Ranran Zhang
Thomas P Loughran
Penn State Milton S. Hershey Medical Center · US

Funding

Survival Mechanisms in Leukemic NK CellsR01CA098472 · NCI · UNIVERSITY OF VIRGINIA · PI LOUGHRAN, THOMAS P. · 2003 to 2016
$4.0M
NCI NIH HHS CA94872NCI NIH HHS R01 CA098472
6 · The paper itself

Abstract

Large granular lymphocyte (LGL) leukemia is a rare disorder of mature cytotoxic T or natural killer cells. Large granular lymphocyte leukemia is characterized by the accumulation of cytotoxic cells in blood and infiltration in the bone marrow, liver, and spleen. Herein, we review clinical features of LGL leukemia. We focus our discussion on known survival signals believed to play a role in the pathogenesis of LGL leukemia and their potential therapeutic implications.

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell DeathCell SurvivalExtracellular Signal-Regulated MAP KinasesFas Ligand ProteinHumansImmunophenotypingLeukemia, Large Granular LymphocyticMedical OncologyMiceSignal TransductionT-LymphocytesTreatment OutcomeAntineoplastic AgentsExtracellular Signal-Regulated MAP KinasesFas Ligand Protein

Identifiers

PMID19778848
PMCPMC4377229
OpenAlexW1998089092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.