ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Incremental value of combining 64-slice computed tomography angiography with stress nuclear myocardial perfusion imaging to improve noninvasive detection of coronary artery disease.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Diagnostic Performance of Hybrid Cardiac Imaging Methods for Assessment of Obstructive Coronary Artery Disease Compared With Stand-Alone Coronary Computed Tomography Angiography: A Meta-Analysis.JACC. Cardiovascular imaging · 2018Pooled it
- The diagnostic performance of coronary artery angiography with 64-MSCT and post 64-MSCT: systematic review and meta-analysis.PloS one · 2014Pooled it
- Use of 3x2 tables with an intention to diagnose approach to assess clinical performance of diagnostic tests: meta-analytical evaluation of coronary CT angiography studies.BMJ (Clinical research ed.) · 2012Pooled it
- Hybrid cardiac imaging: SPECT/CT and PET/CT. A joint position statement by the European Association of Nuclear Medicine (EANM), the European Society of Cardiac Radiology (ESCR) and the European Council of Nuclear Cardiology (ECNC).European journal of nuclear medicine and molecular imaging · 2011Guideline
- The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT).Insights into imaging · 2024Article
- Sequential SPECT/CT imaging for detection of coronary artery disease in a large cohort: evaluation of the need for additional imaging and radiation exposure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Sequential SPECT/CT imaging starting with stress SPECT in patients with left bundle branch block suspected for coronary artery disease.European radiology · 2017Article
- Imaging of coronary atherosclerosis - evolution towards new treatment strategies.Nature reviews. Cardiology · 2016Review
- Article
- Noninvasive cardiac imaging in suspected acute coronary syndrome.Nature reviews. Cardiology · 2016Review
- EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision.European journal of nuclear medicine and molecular imaging · 2015Article
- Molecular imaging of plaques in coronary arteries with PET and SPECT.Journal of geriatric cardiology : JGC · 2014Review
- Coronary plaque imaging by coronary computed tomography angiography.World journal of radiology · 2014Review
- Cardiac hybrid imaging.European journal of nuclear medicine and molecular imaging · 2014Review
- Automatic detection of left and right ventricles from CTA enables efficient alignment of anatomy with myocardial perfusion data.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Multimodality Imaging in Ischemic Cardiomyopathy.Current cardiovascular imaging reports · 2014Review
- Diagnosing coronary artery disease with hybrid PET/CT: it takes two to tango.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Review
- Image-guided therapies for myocardial repair: concepts and practical implementation.European heart journal. Cardiovascular Imaging · 2013Review
- Article
- [Hybrid imaging in diagnostics and therapy of chronic myocardial ischemia. Clinical value].Herz · 2013Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare the accuracy of combined 64-slice computed tomography angiography (CTA) and stress nuclear myocardial perfusion imaging (MPI) in the noninvasive detection of coronary artery disease (CAD) with that of 64-slice CTA alone. METHODS AND
resultsOne hundred thirty symptomatic patients with suspected CAD underwent both 64-slice CTA and stress thallium-201 MPI before invasive coronary angiography (ICA). Coronary lesions with >or=50% luminal narrowing were considered as significant stenoses on CTA and ICA. Of 390 arteries in 130 patients, 54 (14%) were nonevaluable by CTA due to severe calcifications, motion artifacts, and/or poor opacification. All nonevaluable arteries were considered positive. The sensitivity, specificity, PPV and NPV were 95%, 80%, 69%, and 97%, respectively, for CTA alone and 94%, 92%, 85%, and 97%, respectively, for CTA with stress nuclear MPI for all nonevaluable arteries on CTA. Per-patient analysis showed significant increase in specificity and PPV. The majority (75%, 9/12) of nonevaluable severely calcified vessels in the left anterior descending artery were positive on stress nuclear MPI, whereas the majority (89%, 8/9) of nonevaluable vessels with motion artifacts in the right coronary artery were negative.
conclusionsCombined CTA and stress nuclear MPI provide improved diagnostic accuracy for the noninvasive detection of CAD.
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