ArticleBeilstein journal of organic chemistry2009
Mitomycins syntheses: a recent update.
Article in Beilstein journal of organic chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Lignin-Modified Single-Use Graphite Electrodes: Electrochemical Detection of DNA, Mitomycin C, and Their Interaction.Sensors (Basel, Switzerland) · 2025Article
- Ligand engineering of tetra N-heterocyclic carbenes for boosting catalytic aziridination.Dalton transactions (Cambridge, England : 2003) · 2024Article
- Generation of Hydrogen Peroxide in Cancer Cells: Advancing Therapeutic Approaches for Cancer Treatment.Cancers · 2024Review
- A gold(i)-catalysed approach towards harmalidine an elusive alkaloid fromRSC advances · 2022Article
- Sterically Demanding Flexible Phosphoric Acids for Constructing Efficient and Multi-Purpose Asymmetric Organocatalysts.Angewandte Chemie (International ed. in English) · 2022Article
- Sterically Demanding Flexible Phosphoric Acids for Constructing Efficient and Multi-Purpose Asymmetric Organocatalysts.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022Article
- Synthesis of C3,C4-Disubstituted Indoles via the Palladium/Norbornene-CatalyzedOrganic letters · 2021Article
- Drug Combinations in Breast Cancer Therapy.Pharmaceutical nanotechnology · 2019Review
- Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene.Organic letters · 2016Article
- N,N-DIIsopropyl-N-phosphonyl imines lead to efficient asymmetric synthesis of aziridine-2-carboxylic esters.Organic & biomolecular chemistry · 2013Article
- Reactivity of aziridinomitosene derivatives related to FK317 in the presence of protic nucleophiles.The Journal of organic chemistry · 2012Article
- Stereoselective synthesis of complex polycyclic aziridines: use of the Brønsted acid-catalyzed aza-Darzens reaction to prepare an orthogonally protected mitomycin C intermediate with maximal convergency.Chemical communications (Cambridge, England) · 2011Article
- Weapons in disguise--activating mechanisms and protecting group chemistry in nature.Chemistry (Weinheim an der Bergstrasse, Germany) · 2010Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitomycins are a class of very potent antibacterial and anti-cancer compounds having a broad activity against a range of tumours. They have been used in clinics since the 1960's, and the challenges represented by their total synthesis have challenged generations of chemists. Despite these chemical and medicinal features, these compounds, in racemic form, have succumbed to total synthesis only four times over the last 30 years.
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