Evidence map›Paper›PMID 19776378›Full record

GuidelineNeurology2009

Responding to requests from adult patients for neuroenhancements: guidance of the Ethics, Law and Humanities Committee.

Dan Larriviere, Michael A Williams, Matt Rizzo, Richard J Bonnie, AAN Ethics, Law and Humanities Committee

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 137 citations in OpenAlex.

  1. Trial
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  4. Article
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  12. Cosmetic neurology: the role of healthcare professionals.Medicine, health care, and philosophy · 2014
    Article
  13. Review
  14. Article
  15. Article
  16. Should physicians prescribe cognitive enhancers to healthy individuals?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013
    Article
  17. Review
  18. Adderall for All: A Defense of Pediatric Neuroenhancement.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dan LarriviereDepartment of Neurology and School of Law, University of Virginia, Charlottesville, VA 22908, USA. dgl6t@virginia.edu
Michael A Williams
Matt Rizzo
Richard J Bonnie
AAN Ethics, Law and Humanities Committee
Sinai Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, persons who have no diagnosed medical or mental health condition are increasingly seeking and utilizing, for the ostensible purpose of enhancing their memory or cognitive skills, prescription drugs that were originally developed to improve executive function or memory in persons diagnosed with disorders such as attention deficit hyperactivity disorder or Alzheimer disease. Evidence suggests that this practice, now known as neuroenhancement, is gathering momentum. As a result, neurologists may be encountering patients without a diagnosed illness asking for medications with the goal of improving their memory, cognitive focus, or attention span. Strong arguments have been made for and against this practice, often reflecting strongly held convictions concerning the appropriate practice of medicine. The purpose of this report is to provide neurologists with an overview of the ethical, legal, and social issues surrounding the use of pharmaceuticals prescribed to enhance or augment normal cognitive or affective functioning, as well as practical guidance for responding to an adult patient's request for neuroenhancement.

Indexed as

Ethics, MedicalAdultDrug PrescriptionsHumansLiability, LegalNootropic AgentsNootropic Agents

Identifiers

PMID19776378
PMCPMC2769556
OpenAlexW2128698377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.