Evidence map›Paper›PMID 19775771›Full record

SynthesisJournal of hepatology2009

A review of quality of life instruments used in liver transplantation.

Colleen L Jay, Zeeshan Butt, Daniela P Ladner, Anton I Skaro, Michael M Abecassis

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Journal of hepatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06577480 (Investigation of Validity and Reliability of the Turkish Version of the Post-Liver Transplant Quality of Life), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06577480 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Investigation of Validity and Reliability of the Turkish Version of the Post-Liver Transplant Quality of Life (pLTQ) Questionnaire

TypeobservationalSponsorHacettepe UniversityRan2024 to 2026Enrolled80ConditionsLiver Transplant Disorder, Quality of LifeArmsNo intervention
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Quality of Measurement Properties in Patient Reported Outcomes Used in Adult Liver Transplant Candidates and Recipients: a Systematic Review.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. From graft survival to life: redefining success after pediatric liver transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Illness cognitions and health-related quality of life in liver transplant patients related to length of stay, comorbidities and complications.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  9. Quality of life in liver transplant recipients during the Corona virus disease 19 pandemic: A multicentre study.Liver international : official journal of the International Association for the Study of the Liver · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Quality of life 5 years following liver transplantation.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Colleen L JayDivision of Organ Transplantation, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Zeeshan Butt
Daniela P Ladner
Anton I Skaro
Michael M Abecassis

Funding

Transplant Surgery Scientist Training ProgramT32DK077662 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Richard M Green, Daniela P Ladner · 2007 to 2026
$3.8M
NIDDK NIH HHS 5 T32 DK077662-02NIDDK NIH HHS T32 DK077662
6 · The paper itself

Abstract

With improvements in patient and graft survival after liver transplantation, recipient quality of life (QOL) has become an important focus of patient care and clinical outcomes research. To provide a better understanding of the instruments used to assess QOL in the adult liver transplant population, we conducted a systematic review of the MEDLINE database and Cochrane library. Our review identified 128 relevant articles utilizing more than 50 different QOL instruments. Generic health status instruments are the most commonly used, and among them the Medical Outcomes Study Short Form-36 (SF-36), the Hospital Anxiety and Depression Scale (HADS), and the Beck Depression Inventory (BDI) are the most prevalent. Few studies (16%) included targeted, disease-specific instruments. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Quality of Life questionnaire, the Liver Disease Quality of Life questionnaire, and the Chronic Liver Disease questionnaire are the most frequently employed targeted instruments; however, these instruments have been designed to assess QOL in patients with chronic liver disease rather than patients after liver transplantation. The present review focuses on the psychometric properties of the existing QOL instruments and discusses their individual strengths and limitations in evaluating liver transplantation recipients. The lack of a gold-standard QOL instrument for liver transplant recipients is an impediment to cross-study comparisons. We conclude that the development of a QOL instrument specifically for liver transplant recipients will improve QOL assessment in this population leading to a more nuanced understanding of the factors that influence transplant recipients' well-being.

Indexed as

Quality of LifeAdultHealth Status IndicatorsHumansLiver TransplantationPsychometricsSurveys and Questionnaires

Identifiers

PMID19775771
PMCPMC2761971

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.