Evidence map›Paper›PMID 19774384›Full record

ArticleRheumatology international2010

Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin.

Kei Ohnuma, Osamu Hosono, Tomoki Katayose, Noritada Yoshikawa, Hiroshi Kawasaki, Takeshi Fujii, Naoki Oyaizu, Hirotoshi Tanaka, Chikao Morimoto

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Microscopic polyangiitis.Rheumatic diseases clinics of North America · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kei OhnumaDepartment of Rheumatology and Allergy, Research Hospital, Institute of Medical Science, University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.
Osamu Hosono
Tomoki Katayose
Noritada Yoshikawa
Hiroshi Kawasaki
Takeshi Fujii
Naoki Oyaizu
Hirotoshi Tanaka
Chikao Morimoto
Tokyo University of Science · JPThe University of Tokyo · JPTokyo Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report herein a case of microscopic polyangiitis (MPA), presenting onset with a spiking fever, liver/biliary dysfunction without jaundice and calf pain without elevation of serum creatine phosphokinase. During 1 month of careful examinations for initial diagnosis, the patient developed renal dysfunction and pulmonary hemorrhage. Based on the results of positive MPO-ANCA, renal and pulmonary involvements, the patient was diagnosed with MPA and treated with high-dose prednisolone and oral cyclophosphamide. Soon after initiation of the treatment, symptoms such as fever, calf pain, liver/biliary dysfunction and renal dysfunction disappeared with decrease of MPO-ANCA titer to the normal level.

Indexed as

Administration, OralAntibodies, Antineutrophil CytoplasmicCyclophosphamideDose-Response Relationship, DrugFemaleFever of Unknown OriginHumansLegLiver DiseasesMicroscopic PolyangiitisMiddle AgedPainPeroxidasePrednisoloneTreatment OutcomeAntibodies, Antineutrophil CytoplasmicCyclophosphamidePeroxidasePrednisolone

Identifiers

PMID19774384
OpenAlexW2084942977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.