ArticleEuropean journal of nuclear medicine and molecular imaging2010
Coronary calcium score scans for attenuation correction of quantitative PET/CT 13N-ammonia myocardial perfusion imaging.
Article in European journal of nuclear medicine and molecular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- The power of zero calcium in 82-Rubidium PET irrespective of sex and age.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Value of 12-lead electrocardiogram to predict myocardial scar on FDG PET in heart failure patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Best practice for the nuclear medicine technologist in CT-based attenuation correction and calcium score for nuclear cardiology.European journal of hybrid imaging · 2020Review
- Interpolated average CT for cardiac PET/CT attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- De Novo Glutamine Synthesis: Importance for the Proliferation of Glioma Cells and Potentials for Its Detection With 13N-Ammonia.Molecular imaging · 2016Article
- EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision.European journal of nuclear medicine and molecular imaging · 2015Article
- Single low-dose CT scan optimized for rest-stress PET attenuation correction and quantification of coronary artery calcium.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Coronary artery calcium quantification from contrast enhanced CT using gemstone spectral imaging and material decomposition.The international journal of cardiovascular imaging · 2014Article
- Computed tomography calcium score scan for attenuation correction of N-13 ammonia cardiac positron emission tomography: effect of respiratory phase and registration method.The international journal of cardiovascular imaging · 2013Article
- Usefulness of coronary calcium scoring to myocardial perfusion SPECT in the diagnosis of coronary artery disease in a predominantly high risk population.The international journal of cardiovascular imaging · 2013Article
- Hypodense regions in unenhanced CT identify nonviable myocardium: validation versus 18F-FDG PET.European journal of nuclear medicine and molecular imaging · 2012Article
- PET: Is myocardial flow quantification a clinical reality?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012Review
- Zero coronary calcium in the presence of severe isolated left main stenosis detected by CT coronary angiography in a patient with typical angina and equivocal myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012Article
- Quantitative cardiac positron emission tomography: the time is coming!Scientifica · 2012Review
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to evaluate whether ECG-triggered coronary calcium scoring (CCS) scans can be used for attenuation correction (AC) to quantify myocardial blood flow (MBF) and coronary flow reserve (CFR) assessed by PET/CT with (13)N-ammonia.
methodsThirty-five consecutive patients underwent a (13)N-ammonia PET/CT scan at rest and during standard adenosine stress. MBF values were calculated using AC maps obtained from the ECG-triggered CCS scan during inspiration and validated against MBF values calculated using standard non-gated transmission scans for AC. CFR was calculated as the ratio of hyperaemic over resting MBF. In all 35 consecutive patients intraobserver variability was assessed by blinded repeat analysis for both AC methods.
resultsThere was an excellent correlation between CT AC and CCS for global MBF values at rest (n = 35, r = 0.94, p < 0.001) and during stress (n = 35, r = 0.97, p < 0.001) with narrow Bland-Altman (BA) limits of agreement (-0.21 to 0.10 ml/min per g and -0.41 to 0.30 ml/min per g) as well as for global CFR (n = 35, r = 0.96, p < 0.001, BA -0.27 to 0.34). The excellent correlation was preserved on the segmental MBF analysis for both rest and stress (n = 1190, r = 0.93, p < 0.001, BA -0.60 to 0.50) and for CFR (n = 595, r = 0.87, p < 0.001, BA -0.71 to 0.74). In addition, reproducibility proved excellent for global CFR by CT AC (n = 35, r = 0.91, p < 0.001, BA -0.42-0.58) and CCS scans (n = 35, r = 0.94, p < 0.001, BA -0.34-0.45).
conclusionUse of attenuation maps from CCS scans allows accurate quantitative MBF and CFR assessment with (13)N-ammonia PET/CT.
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